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FOAMV:GAG
Contents
| Species (Taxon ID) | Human spumaretrovirus (SFVcpz(hu)) (Human foamy virus). (11963) | |
| Gene Name(s) | gag | |
| Protein Name(s) | Gag polyprotein
Pr71Gag Gag protein p68Gag p3 p3Gag | |
| External Links | ||
| UniProt | P14349 | |
| EMBL | M19427 U21247 | |
| PDB | 4JNH | |
| PDBsum | 4JNH | |
| Proteomes | UP000008228 | |
| GO | GO:0030430 GO:0042025 GO:0044163 GO:0019013 GO:0003677 GO:0003723 GO:0075521 GO:0039702 GO:0046718 GO:0019076 | |
| InterPro | IPR004957 | |
| Pfam | PF03276 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0044163 |
host cytoskeleton |
ECO:0000315 |
C |
Fig. 2CD and Fig. 4EF |
complete | |||||
| GO:0039715 |
nuclear viral factory |
ECO:0000314 |
C |
Figure1.C. After methanol fixation, cells that were expressing GFP or GFP-GagGRII were examined for intrinsic fluorescence. Nuclei are stained with DAPI. Original magnification ×40. Red arrows indicate a cell undergoing mitosis |
complete | |||||
| GO:0044094 |
host cell nuclear part |
ECO:0000314 |
C |
Figure1.C. After methanol fixation, cells that were expressing GFP or GFP-GagGRII were examined for intrinsic fluorescence. Nuclei are stained with DAPI. Original magnification ×40. Red arrows indicate a cell undergoing mitosis |
complete | |||||
| GO:0005737 |
cytoplasm |
ECO:0000314 |
C |
Figure1.D. Subcellular localization of GagWT and GagG110V in Hela transfected cells with GagWT or GagG110V and analyzed, 24 h post-transfection, by confocal microscopy following indirect immunofluorescence using rabbit polyclonal anti-PFV. GagWT. |
complete | |||||
| GO:0044444 |
cytoplasmic part |
ECO:0000314 |
C |
Figure1.D. Subcellular localization of GagWT and GagG110V in Hela transfected cells with GagWT or GagG110V and analyzed, 24 h post-transfection, by confocal microscopy following indirect immunofluorescence using rabbit polyclonal anti-PFV. GagWT. |
complete | |||||
| GO:0033655 |
host cell cytoplasm part |
ECO:0000314 |
C |
Figure1.D. Subcellular localization of GagWT and GagG110V in Hela transfected cells with GagWT or GagG110V and analyzed, 24 h post-transfection, by confocal microscopy following indirect immunofluorescence using rabbit polyclonal anti-PFV. GagWT. |
complete | |||||
|
part_of |
GO:0044163 |
host cytoskeleton |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
| GO:0000787 |
cytoplasmic nucleosome |
ECO:0000314 |
C |
Figure1.D. Subcellular localization of GagWT and GagG110V in Hela transfected cells with GagWT or GagG110V and analyzed, 24 h post-transfection, by confocal microscopy following indirect immunofluorescence using rabbit polyclonal anti-PFV. GagWT. |
complete | |||||
|
part_of |
GO:0019028 |
viral capsid |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019076 |
viral release from host cell |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030430 |
host cell cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0044163 |
host cytoskeleton |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046718 |
viral entry into host cell |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0075521 |
microtubule-dependent intracellular transport of viral material towards nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019012 |
virion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016032 |
viral process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030430 |
host cell cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019028 |
viral capsid |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0075521 |
microtubule-dependent intracellular transport of viral material towards nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046755 |
viral budding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046718 |
viral entry into host cell |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0075606 |
transport of viral material towards nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039702 |
viral budding via host ESCRT complex |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019013 |
viral nucleocapsid |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Yu, SF et al. (2011) The DEAD-box RNA helicase DDX6 is required for efficient encapsidation of a retroviral genome. PLoS Pathog. 7 e1002303 PubMed GONUTS page
- ↑ 2.0 2.1 Tobaly-Tapiero, J et al. (2012) Investigating the intercellular spreading properties of the foamy virus Gag protein. PLoS ONE 7 e31108 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Renault, N et al. (2011) A nuclear export signal within the structural Gag protein is required for prototype foamy virus replication. Retrovirology 8 6 PubMed GONUTS page
