EEEV:Q66579

Species (Taxon ID)	Eastern equine encephalitis virus (EEEV) (Eastern equineencephalomyelitis virus). (11021)
Gene Name(s)	No Information Provided.
Protein Name(s)	Eastern Equine Encephalomyelitis Virus RNA sequence (ECO:0000313 with EMBL:CAA44845.1)
External Links
UniProt	Q66579
EMBL	X63135
PIR	D37264 S26373
RefSeq	NP_632022.1
ProteinModelPortal	Q66579
GeneID	944522
GO	GO:0033644 GO:0016021 GO:0019028 GO:0055036 GO:0004252 GO:0005198 GO:0039654 GO:0019062
Gene3D	2.60.40.350 2.60.98.10
InterPro	IPR002548 IPR000936 IPR002533 IPR000336 IPR011998 IPR013754 IPR014756 IPR000930 IPR009003
Pfam	PF01589 PF00943 PF01563 PF00944
PRINTS	PR00798
SUPFAM	SSF50494 SSF56983 SSF81296
PROSITE	PS51690

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0039653	suppression by virus of host transcription	PMID:17267491	ECO:0000314			P		Figure 2 shows that the EEEV capsid protein is an inhibitor of gene expression.	complete CACAO 9605
	GO:0006468	protein phosphorylation	PMID:17267491	ECO:0000314			P		Fig. 4: 293T cells were cotransfected with luciferase reporter plasmid and either empty vector or plasmid expressing EEEV capsid/entire EEEV structural polyprotein/LaCrosse virus NSs, phophorylated eIF2a appeared most prominantly in cells expressing EEEV capsid	complete CACAO 9699
	GO:0039501	suppression by virus of host type I interferon production	PMID:17267491	ECO:0000314			P		Fig. 2A: cells were transfected with an IFN-beta-promoter-CAT-reporter plasmid and either an empty vector or a capsid expression plasmid, cells expressing the capsid had lower CAT levels, indicating the inhibition of IFN-beta promoter expression	complete CACAO 9928
involved_in	GO:0039501	suppression by virus of host type I interferon production	PMID:17267491	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0039653	suppression by virus of host transcription	PMID:17267491	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0004252	serine-type endopeptidase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000930 InterPro:IPR002533 InterPro:IPR002548	F		Seeded From UniProt	complete
enables	GO:0005198	structural molecule activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000936	F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000930	P		Seeded From UniProt	complete
part_of	GO:0019028	viral capsid	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000936 InterPro:IPR002533 InterPro:IPR002548	C		Seeded From UniProt	complete
part_of	GO:0055036	virion membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002533 InterPro:IPR002548	C		Seeded From UniProt	complete
part_of	GO:0019028	viral capsid	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0167	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0645	P		Seeded From UniProt	complete
involved_in	GO:0046718	viral entry into host cell	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1160	P		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0645	F		Seeded From UniProt	complete
involved_in	GO:0019062	virion attachment to host cell	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1161	P		Seeded From UniProt	complete
involved_in	GO:0039663	membrane fusion involved in viral entry into host cell	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1168	P		Seeded From UniProt	complete
part_of	GO:0019012	virion	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0946	C		Seeded From UniProt	complete
enables	GO:0008236	serine-type peptidase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0720	F		Seeded From UniProt	complete
involved_in	GO:0016032	viral process	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0945	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
involved_in	GO:0039654	fusion of virus membrane with host endosome membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1170	P		Seeded From UniProt	complete
part_of	GO:0030430	host cell cytoplasm	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1035	C		Seeded From UniProt	complete
part_of	GO:0033644	host cell membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1043	C		Seeded From UniProt	complete
involved_in	GO:0046718	viral entry into host cell	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1162	P		Seeded From UniProt	complete
part_of	GO:0055036	virion membrane	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0275	C		Seeded From UniProt	complete
part_of	GO:0030430	host cell cytoplasm	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0381	C		Seeded From UniProt	complete
enables	GO:0004252	serine-type endopeptidase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000416659	F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000416659	P		Seeded From UniProt	complete
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