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EDWTA:A2TEZ4

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Species (Taxon ID) Edwardsiella tarda. (636)
Gene Name(s) fur (ECO:0000313 with EMBL:ABM89104.1)
Protein Name(s) Ferric uptake regulator (ECO:0000313 with EMBL:ABM89104.1)
External Links
UniProt A2TEZ4
EMBL EF197912
RefSeq WP_034168655.1
ProteinModelPortal A2TEZ4
STRING 498217.ETAE_2610
eggNOG ENOG41090R7
COG0735
GO GO:0003677
GO:0046872
GO:0003700
CDD cd07153
Gene3D 1.10.10.10
InterPro IPR002481
IPR011991
Pfam PF01475
SUPFAM SSF46785

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0040010

positive regulation of growth rate

PMID:27102497[1]

ECO:0000315

P

Fig. 1. Growth analysis of Edwardsiella tarda TX01 showed faster growth rate than TX01Δfur (ferric uptake regulator) mutant

complete
CACAO 12323

GO:1900705

negative regulation of siderophore biosynthetic process

PMID:27102497[1]

ECO:0000315

P

Fig. 2 Chromoazurol S (CAS) assay compares siderophore production of Edwardsiella tarda TX01 and TX01Δfur. TX01Δfur (Ferric uptake regulator) mutant had increased siderophore production.

complete
CACAO 12324

GO:0009405

pathogenesis

PMID:27102497[1]

ECO:0000315

P

Fig. 4a. In vivo infection study: Turbot (flatfish) were infected with a dose of Edwardsiella tarda TX01, TX01Δfur, or TX01ΔfurC. Plate counts of bacteria recovered from organs of TX01Δfur-infected fish were significantly lower than the TX01-infected fish at 24 and 48 hours post infection.

complete
CACAO 12348

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002481

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002481

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000481764

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000481764

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Hu, YH & Sun, L (2016) The global regulatory effect of Edwardsiella tarda Fur on iron acquisition, stress resistance, and host infection: A proteomics-based interpretation. J Proteomics 140 100-10 PubMed GONUTS page