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ECOLX:IUCA

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Species (Taxon ID) Escherichia coli. (562)
Gene Name(s) iucA
Protein Name(s) N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase

Aerobactin synthase IucA

External Links
UniProt Q47316
EMBL X76100
PIR S44018
PRIDE Q47316
eggNOG COG4264
BioCyc MetaCyc:MONOMER-11597
UniPathway UPA00014
GO GO:0050565
GO:0005524
GO:0015343
GO:0016740
GO:0019270
GO:0055072
GO:0019290
InterPro IPR007310
IPR022770
Pfam PF06276
PF04183

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009405

pathogenesis

PMID:23460907[1]

ECO:0000315

P

Figure 5. Colonization and persistence of wild-type strain Escherichia coli E058 and its mutant E058∆ iucA. The ability of E058 ∆iucA to colonize was significantly less than the wild-type in tissue samples from an individual chicken

complete
CACAO 12393

involved_in

GO:0055072

iron ion homeostasis

PMID:3087960[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0050565

aerobactin synthase activity

PMID:3087960[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0019270

aerobactin biosynthetic process

PMID:3087960[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0019290

siderophore biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007310
InterPro:IPR037455

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0016874

ligase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0436

F

Seeded From UniProt

complete

involved_in

GO:0019270

aerobactin biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00014

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Ling, J et al. (2013) Aerobactin synthesis genes iucA and iucC contribute to the pathogenicity of avian pathogenic Escherichia coli O2 strain E058. PLoS ONE 8 e57794 PubMed GONUTS page
  2. 2.0 2.1 2.2 de Lorenzo, V & Neilands, JB (1986) Characterization of iucA and iucC genes of the aerobactin system of plasmid ColV-K30 in Escherichia coli. J. Bacteriol. 167 350-5 PubMed GONUTS page