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ECOLI:XGPT

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) gpt (synonyms: gpp, gxu)
Protein Name(s) Xanthine phosphoribosyltransferase

Xanthine-guanine phosphoribosyltransferase XGPRT

External Links
UniProt P0A9M5
EMBL X00221
X00222
M13422
M12907
M15035
U70214
U00096
AP009048
M10382
PIR A00587
RefSeq NP_414773.1
YP_488533.1
PDB 1A95
1A96
1A97
1A98
1NUL
PDBsum 1A95
1A96
1A97
1A98
1NUL
ProteinModelPortal P0A9M5
SMR P0A9M5
IntAct P0A9M5
STRING 511145.b0238
SWISS-2DPAGE P0A9M5
PaxDb P0A9M5
PRIDE P0A9M5
EnsemblBacteria AAC73342
BAA77907
GeneID 12931995
944817
KEGG ecj:Y75_p0229
eco:b0238
PATRIC 32115591
EchoBASE EB0409
EcoGene EG10414
eggNOG COG0503
HOGENOM HOG000226805
InParanoid P0A9M5
KO K00769
OMA WDQLHRD
OrthoDB EOG6H1Q23
PhylomeDB P0A9M5
BioCyc EcoCyc:GPT-MONOMER
ECOL316407:JW0228-MONOMER
MetaCyc:GPT-MONOMER
UniPathway UPA00602
EvolutionaryTrace P0A9M5
PRO PR:P0A9M5
Proteomes UP000000318
UP000000625
Genevestigator P0A9M5
GO GO:0005829
GO:0005886
GO:0004422
GO:0000287
GO:0000310
GO:0032263
GO:0032264
GO:0032265
Gene3D 3.40.50.2020
HAMAP MF_01903
InterPro IPR000836
IPR029057
IPR023747
Pfam PF00156
SUPFAM SSF53271
PROSITE PS00103

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005829

cytosol

PMID:16858726[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0032265

XMP salvage

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10414
PANTHER:PTN002218367

P

Seeded From UniProt

complete

involved_in

GO:0032264

IMP salvage

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10414
PANTHER:PTN002218367

P

Seeded From UniProt

complete

involved_in

GO:0032263

GMP salvage

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10414
PANTHER:PTN002218367

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10414
PANTHER:PTN002218367

C

Seeded From UniProt

complete

enables

GO:0004422

hypoxanthine phosphoribosyltransferase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10414
PANTHER:PTN002218367

F

Seeded From UniProt

complete

enables

GO:0000310

xanthine phosphoribosyltransferase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10414
PANTHER:PTN002218367

F

Seeded From UniProt

complete

involved_in

GO:0032265

XMP salvage

PMID:820683[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0032264

IMP salvage

PMID:6305942[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0032263

GMP salvage

PMID:820683[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18304323[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0004422

hypoxanthine phosphoribosyltransferase activity

PMID:6305942[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000310

xanthine phosphoribosyltransferase activity

PMID:6305942[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000310

xanthine phosphoribosyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR023747

F

Seeded From UniProt

complete

involved_in

GO:0009116

nucleoside metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000836

P

Seeded From UniProt

complete

enables

GO:0000310

xanthine phosphoribosyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.4.2.22

F

Seeded From UniProt

complete

involved_in

GO:0006166

purine ribonucleoside salvage

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000087094

P

Seeded From UniProt

complete

enables

GO:0000287

magnesium ion binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000087094

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000087094

C

Seeded From UniProt

complete

enables

GO:0000310

xanthine phosphoribosyltransferase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000087094

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-KW:KW-0997
UniProtKB-SubCell:SL-0037

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0016757

transferase activity, transferring glycosyl groups

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0328

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0006166

purine ribonucleoside salvage

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0660

P

Seeded From UniProt

complete

involved_in

GO:0032265

XMP salvage

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00602

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. 3.0 3.1 Holden, JA et al. (1976) Escherichia coli mutants deficient in guanine-xanthine phosphoribosyltransferase. J. Bacteriol. 126 1141-8 PubMed GONUTS page
  4. 4.0 4.1 4.2 Liu, SW & Milman, G (1983) Purification and characterization of Escherichia coli guanine-xanthine phosphoribosyltransferase produced by a high efficiency expression plasmid utilizing a lambda PL promoter and CI857 temperature-sensitive repressor. J. Biol. Chem. 258 7469-75 PubMed GONUTS page
  5. Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page