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ECOLI:SRP54

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) ffh (ECO:0000255 with HAMAP-Rule:MF_00306)
Protein Name(s) Signal recognition particle protein (ECO:0000255 with HAMAP-Rule:MF_00306)

Fifty-four homolog (ECO:0000255 with HAMAP-Rule:MF_00306) Ffh p48

External Links
UniProt P0AGD7
EMBL X01818
U00096
AP009048
PIR E65039
RefSeq NP_417101.1
YP_490833.1
PDB 1DUL
1HQ1
2J28
2PXB
2PXD
2PXE
2PXF
2PXK
2PXL
2PXP
2PXQ
2PXT
2PXU
2PXV
2XKV
2XXA
3LQX
4C7O
PDBsum 1DUL
1HQ1
2J28
2PXB
2PXD
2PXE
2PXF
2PXK
2PXL
2PXP
2PXQ
2PXT
2PXU
2PXV
2XKV
2XXA
3LQX
4C7O
ProteinModelPortal P0AGD7
SMR P0AGD7
DIP DIP-31865N
IntAct P0AGD7
MINT MINT-1218614
STRING 511145.b2610
TCDB 3.A.5.1.1
PaxDb P0AGD7
PRIDE P0AGD7
EnsemblBacteria AAC75659
BAA16495
GeneID 12933092
947102
KEGG ecj:Y75_p2558
eco:b2610
PATRIC 32120619
EchoBASE EB0296
EcoGene EG10300
eggNOG COG0541
HOGENOM HOG000036164
InParanoid P0AGD7
KO K03106
OMA MLPGMGQ
OrthoDB EOG62K1ZH
PhylomeDB P0AGD7
BioCyc EcoCyc:EG10300-MONOMER
ECOL316407:JW5414-MONOMER
EvolutionaryTrace P0AGD7
PRO PR:P0AGD7
Proteomes UP000000318
UP000000625
Genevestigator P0AGD7
GO GO:0030529
GO:0048500
GO:0008312
GO:0005525
GO:0003924
GO:0006184
GO:0006612
GO:0006614
Gene3D 1.10.260.30
3.40.50.300
HAMAP MF_00306
InterPro IPR003593
IPR027417
IPR013822
IPR004125
IPR022941
IPR000897
IPR004780
PANTHER PTHR11564:SF7
Pfam PF00448
PF02881
PF02978
SMART SM00382
SM00962
SM00963
SUPFAM SSF47446
SSF52540
TIGRFAMs TIGR00959
PROSITE PS00300

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:1990904

ribonucleoprotein complex

PMID:1701272[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0048500

signal recognition particle

PMID:1701272[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0048500

signal recognition particle

PMID:1331806[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006612

protein targeting to membrane

PMID:1331806[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

PMID:7612669[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18304323[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

PMID:7612669[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

PMID:7612669[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004780
InterPro:IPR022941

F

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000897
InterPro:IPR004780
InterPro:IPR013822
InterPro:IPR022941

F

Seeded From UniProt

complete

involved_in

GO:0006614

SRP-dependent cotranslational protein targeting to membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000897
InterPro:IPR004125
InterPro:IPR004780
InterPro:IPR013822
InterPro:IPR022941
InterPro:IPR036891

P

Seeded From UniProt

complete

enables

GO:0008312

7S RNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004125
InterPro:IPR036891

F

Seeded From UniProt

complete

part_of

GO:0048500

signal recognition particle

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004125
InterPro:IPR004780
InterPro:IPR022941
InterPro:IPR036891

C

Seeded From UniProt

complete

involved_in

GO:0006612

protein targeting to membrane

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000083187

P

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000083187

F

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000083187

F

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000083187

F

Seeded From UniProt

complete

part_of

GO:1990904

ribonucleoprotein complex

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000083187

C

Seeded From UniProt

complete

part_of

GO:0048500

signal recognition particle

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000083187

C

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0342

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Poritz, MA et al. (1990) An E. coli ribonucleoprotein containing 4.5S RNA resembles mammalian signal recognition particle. Science 250 1111-7 PubMed GONUTS page
  2. 2.0 2.1 Phillips, GJ & Silhavy, TJ (1992) The E. coli ffh gene is necessary for viability and efficient protein export. Nature 359 744-6 PubMed GONUTS page
  3. 3.0 3.1 3.2 Samuelsson, T et al. (1995) The GTPase activity of the Escherichia coli Ffh protein is important for normal growth. Biochim. Biophys. Acta 1267 83-91 PubMed GONUTS page
  4. Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page