GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

ECOLI:PTHP

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) ptsH (synonyms: hpr)
Protein Name(s) Phosphocarrier protein HPr

Histidine-containing protein

External Links
UniProt P0AA04
EMBL M10425
J02796
M21994
M21451
U00096
AP009048
PIR A29785
RefSeq NP_416910.1
YP_490651.1
PDB 1CM2
1CM3
1GGR
1HDN
1J6T
1OPD
1PFH
1POH
1VRC
2JEL
2LRK
2LRL
2XDF
3CCD
3EZA
3EZB
3EZE
PDBsum 1CM2
1CM3
1GGR
1HDN
1J6T
1OPD
1PFH
1POH
1VRC
2JEL
2LRK
2LRL
2XDF
3CCD
3EZA
3EZB
3EZE
ProteinModelPortal P0AA04
SMR P0AA04
DIP DIP-35731N
IntAct P0AA04
MINT MINT-8085981
STRING 511145.b2415
TCDB 8.A.8.1.1
PhosSite P0810427
SWISS-2DPAGE P0AA04
PaxDb P0AA04
PRIDE P0AA04
EnsemblBacteria AAC75468
BAA16289
GeneID 12930706
946886
KEGG ecj:Y75_p2376
eco:b2415
PATRIC 32120213
EchoBASE EB0781
EcoGene EG10788
eggNOG COG1925
HOGENOM HOG000278399
InParanoid P0AA04
KO K02784
OMA YQGKDVN
OrthoDB EOG6XDGX2
PhylomeDB P0AA04
BioCyc EcoCyc:PTSH-MONOMER
ECOL316407:JW2408-MONOMER
MetaCyc:PTSH-MONOMER
EvolutionaryTrace P0AA04
PRO PR:P0AA04
Proteomes UP000000318
UP000000625
Genevestigator P0AA04
GO GO:0019197
GO:0008047
GO:0016301
GO:0008965
GO:0004674
GO:0009401
GO:0043085
GO:0045819
Gene3D 3.30.1340.10
InterPro IPR000032
IPR001020
IPR002114
Pfam PF00381
PRINTS PR00107
SUPFAM SSF55594
TIGRFAMs TIGR01003
PROSITE PS51350
PS00369
PS00589

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0008047

enzyme activator activity

PMID:9334229[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0045819

positive regulation of glycogen catabolic process

PMID:9334229[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0019197

phosphoenolpyruvate-dependent sugar phosphotransferase complex

PMID:5545082[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

PMID:4942330[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0009401

phosphoenolpyruvate-dependent sugar phosphotransferase system

PMID:5545082[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008965

phosphoenolpyruvate-protein phosphotransferase activity

PMID:5545082[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18304323[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

GO:0042327

positive regulation of phosphorylation

PMID:11350937[5]

ECO:0000314

P

See Figure 4B.

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0016301

P

Seeded From UniProt

complete

involved_in

GO:0043085

positive regulation of catalytic activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008047

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0008643

carbohydrate transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0762

P

Seeded From UniProt

complete

involved_in

GO:0009401

phosphoenolpyruvate-dependent sugar phosphotransferase system

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0598

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Seok, YJ et al. (1997) High affinity binding and allosteric regulation of Escherichia coli glycogen phosphorylase by the histidine phosphocarrier protein, HPr. J. Biol. Chem. 272 26511-21 PubMed GONUTS page
  2. 2.0 2.1 2.2 Kundig, W & Roseman, S (1971) Sugar transport. I. Isolation of a phosphotransferase system from Escherichia coli. J. Biol. Chem. 246 1393-406 PubMed GONUTS page
  3. Anderson, B et al. (1971) Sugar transport. 3. Purification and properties of a phosphocarrier protein (HPr) of the phosphoenolpyruvate-dependent phosphotransferase system of Escherichia coli. J. Biol. Chem. 246 7023-33 PubMed GONUTS page
  4. Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
  5. Gutknecht, R et al. (2001) The dihydroxyacetone kinase of Escherichia coli utilizes a phosphoprotein instead of ATP as phosphoryl donor. EMBO J. 20 2480-6 PubMed GONUTS page