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ECOLI:MLTD

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) mltD (synonyms: dniR, yafG)
Protein Name(s) Membrane-bound lytic murein transglycosylase D

Murein hydrolase D Regulatory protein DniR

External Links
UniProt P0AEZ7
EMBL U70214
U00096
AP009048
X60739
PIR E64745
RefSeq NP_414747.1
YP_488508.1
PDB 1E0G
PDBsum 1E0G
ProteinModelPortal P0AEZ7
SMR P0AEZ7
DIP DIP-48010N
IntAct P0AEZ7
STRING 511145.b0211
PaxDb P0AEZ7
PRIDE P0AEZ7
EnsemblBacteria AAC73316
BAA77882
GeneID 12932474
945694
KEGG ecj:Y75_p0202
eco:b0211
PATRIC 32115535
EchoBASE EB0242
EcoGene EG10246
eggNOG COG0741
HOGENOM HOG000258639
InParanoid P0AEZ7
KO K08307
OMA YNPAYNQ
OrthoDB EOG6038ZC
PhylomeDB P0AEZ7
BioCyc EcoCyc:EG10246-MONOMER
ECOL316407:JW5018-MONOMER
MetaCyc:EG10246-MONOMER
EvolutionaryTrace P0AEZ7
PRO PR:P0AEZ7
Proteomes UP000000318
UP000000625
Genevestigator P0AEZ7
GO GO:0009279
GO:0016020
GO:0005886
GO:0016837
GO:0008933
GO:0071555
GO:0000270
GO:0051353
Gene3D 3.10.350.10
InterPro IPR018392
IPR023346
IPR008258
IPR000189
Pfam PF01476
PF01464
SMART SM00257
SUPFAM SSF53955
SSF54106
PROSITE PS51257
PS00922

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0008932

lytic endotransglycosylase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10246
PANTHER:PTN002330604

F

Seeded From UniProt

complete

involved_in

GO:0051353

positive regulation of oxidoreductase activity

PMID:1663890[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:10843862[3]

ECO:0000303

author statement without traceable support used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0008933

lytic transglycosylase activity

PMID:10843862[3]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008933

lytic transglycosylase activity

PMID:23421439[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008933

lytic transglycosylase activity

PMID:10843862[3]

ECO:0000245

automatically integrated combinatorial evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008932

lytic endotransglycosylase activity

PMID:23421439[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0000270

peptidoglycan metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000189

P

Seeded From UniProt

complete

enables

GO:0008933

lytic transglycosylase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000189

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000189

C

Seeded From UniProt

complete

part_of

GO:0030288

outer membrane-bounded periplasmic space

PMID:15174130[5]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

involved_in

GO:0071555

cell wall organization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0961

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Kajie, S et al. (1991) Molecular cloning and DNA sequence of dniR, a gene affecting anaerobic expression of the Escherichia coli hexaheme nitrite reductase. FEMS Microbiol. Lett. 67 205-11 PubMed GONUTS page
  3. 3.0 3.1 3.2 Bateman, A & Bycroft, M (2000) The structure of a LysM domain from E. coli membrane-bound lytic murein transglycosylase D (MltD). J. Mol. Biol. 299 1113-9 PubMed GONUTS page
  4. 4.0 4.1 Lee, M et al. (2013) Reactions of all Escherichia coli lytic transglycosylases with bacterial cell wall. J. Am. Chem. Soc. 135 3311-4 PubMed GONUTS page
  5. Gonnet, P et al. (2004) Fine-tuning the prediction of sequences cleaved by signal peptidase II: a curated set of proven and predicted lipoproteins of Escherichia coli K-12. Proteomics 4 1597-613 PubMed GONUTS page