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ECOLI:MDTG

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) mdtG (synonyms: yceE)
Protein Name(s) Multidrug resistance protein MdtG
External Links
UniProt P25744
EMBL X59939
U00096
AP009048
PIR B42290
RefSeq NP_415571.1
YP_489321.1
ProteinModelPortal P25744
STRING 511145.b1053
TCDB 2.A.1.2.20
PRIDE P25744
DNASU 945627
EnsemblBacteria AAC74137
BAA35851
GeneID 12932512
945627
KEGG ecj:Y75_p1023
eco:b1053
PATRIC 32117343
EchoBASE EB1319
EcoGene EG11343
eggNOG COG0477
HOGENOM HOG000066093
InParanoid P25744
KO K08161
OMA FIHERKI
OrthoDB EOG6VF34T
PhylomeDB P25744
BioCyc EcoCyc:YCEE-MONOMER
ECOL316407:JW1040-MONOMER
PRO PR:P25744
Proteomes UP000000318
UP000000625
Genevestigator P25744
GO GO:0005887
GO:0022857
GO:0006855
GO:0046677
HAMAP MF_01528
InterPro IPR011701
IPR020846
IPR023692
IPR001958
Pfam PF07690
PRINTS PR01035
SUPFAM SSF103473
PROSITE PS50850

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006855

drug transmembrane transport

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11343
PANTHER:PTN001921125

P

Seeded From UniProt

complete

GO:0005887

integral to plasma membrane

PMID:2545678[2]

ECO:0000255

PMID:7108955[3]


C

Fig. 1 shows the hydropathy plot of TetA (Multidrug resistance protein MdtG), indicating it is an integral protein to the plasma membrane.

complete
CACAO 8775

involved_in

GO:0006855

drug transmembrane transport

PMID:11566977[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005215

transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001958
InterPro:IPR023692

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR023692

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011701

C

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011701

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000055580

C

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000055580

P

Seeded From UniProt

complete

enables

GO:0022857

transmembrane transporter activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000055580

F

Seeded From UniProt

complete

involved_in

GO:0046677

response to antibiotic

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0046

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0997
UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0037

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Eckert, B & Beck, CF (1989) Topology of the transposon Tn10-encoded tetracycline resistance protein within the inner membrane of Escherichia coli. J. Biol. Chem. 264 11663-70 PubMed GONUTS page
  3. Kyte, J & Doolittle, RF (1982) A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157 105-32 PubMed GONUTS page
  4. Nishino, K & Yamaguchi, A (2001) Analysis of a complete library of putative drug transporter genes in Escherichia coli. J. Bacteriol. 183 5803-12 PubMed GONUTS page