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ECOLI:LPXB
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | lpxB (synonyms: pgsB) | |
| Protein Name(s) | Lipid-A-disaccharide synthase | |
| External Links | ||
| UniProt | P10441 | |
| EMBL | M19334 U70214 U00096 AP009048 | |
| PIR | F64742 | |
| RefSeq | NP_414724.1 YP_488484.1 | |
| ProteinModelPortal | P10441 | |
| DIP | DIP-10122N | |
| IntAct | P10441 | |
| MINT | MINT-1246245 | |
| STRING | 511145.b0182 | |
| CAZy | GT19 | |
| PaxDb | P10441 | |
| PRIDE | P10441 | |
| DNASU | 944838 | |
| EnsemblBacteria | AAC73293 BAA77857 | |
| GeneID | 12931876 944838 | |
| KEGG | ecj:Y75_p0178 eco:b0182 | |
| PATRIC | 32115475 | |
| EchoBASE | EB0541 | |
| EcoGene | EG10546 | |
| eggNOG | COG0763 | |
| HOGENOM | HOG000018003 | |
| InParanoid | P10441 | |
| KO | K00748 | |
| OMA | QPWVGLP | |
| OrthoDB | EOG6FBWZR | |
| PhylomeDB | P10441 | |
| BioCyc | EcoCyc:LIPIDADISACCHARIDESYNTH-MONOMER ECOL316407:JW0177-MONOMER MetaCyc:LIPIDADISACCHARIDESYNTH-MONOMER | |
| UniPathway | UPA00359 | |
| PRO | PR:P10441 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P10441 | |
| GO | GO:0005737 GO:0005829 GO:0019897 GO:0008915 GO:0005543 GO:0009245 | |
| HAMAP | MF_00392 | |
| InterPro | IPR003835 | |
| Pfam | PF02684 | |
| TIGRFAMs | TIGR00215 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0009245 |
lipid A biosynthetic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10546 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10546 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005543 |
phospholipid binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10546 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0019897 |
extrinsic component of plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009245 |
lipid A biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009245 |
lipid A biosynthetic process |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008915 |
lipid-A-disaccharide synthase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005543 |
phospholipid binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019897 |
extrinsic component of plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008915 |
lipid-A-disaccharide synthase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009245 |
lipid A biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008915 |
lipid-A-disaccharide synthase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008915 |
lipid-A-disaccharide synthase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000035397 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009245 |
lipid A biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000035397 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016757 |
transferase activity, transferring glycosyl groups |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009245 |
lipid A biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006629 |
lipid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 2.0 2.1 Metzger, LE 4th & Raetz, CR (2009) Purification and characterization of the lipid A disaccharide synthase (LpxB) from Escherichia coli, a peripheral membrane protein. Biochemistry 48 11559-71 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Ray, BL et al. (1984) The biosynthesis of gram-negative endotoxin. Formation of lipid A disaccharides from monosaccharide precursors in extracts of Escherichia coli. J. Biol. Chem. 259 4852-9 PubMed GONUTS page
- ↑ Crowell, DN et al. (1986) Molecular cloning of the genes for lipid A disaccharide synthase and UDP-N-acetylglucosamine acyltransferase in Escherichia coli. J. Bacteriol. 168 152-9 PubMed GONUTS page
- ↑ Radika, K & Raetz, CR (1988) Purification and properties of lipid A disaccharide synthase of Escherichia coli. J. Biol. Chem. 263 14859-67 PubMed GONUTS page
