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ECOLI:LDHD
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | ldhA (synonyms: hslI, htpH) | |
| Protein Name(s) | D-lactate dehydrogenase
D-LDH Fermentative lactate dehydrogenase | |
| External Links | ||
| UniProt | P52643 | |
| EMBL | U36928 U00096 AP009048 | |
| PIR | G64888 | |
| RefSeq | NP_415898.1 YP_489649.1 | |
| ProteinModelPortal | P52643 | |
| SMR | P52643 | |
| DIP | DIP-10087N | |
| IntAct | P52643 | |
| STRING | 511145.b1380 | |
| PaxDb | P52643 | |
| PRIDE | P52643 | |
| EnsemblBacteria | AAC74462 BAA14990 | |
| GeneID | 12930508 946315 | |
| KEGG | ecj:Y75_p1357 eco:b1380 | |
| PATRIC | 32118046 | |
| EchoBASE | EB2978 | |
| EcoGene | EG13186 | |
| eggNOG | COG1052 | |
| HOGENOM | HOG000136695 | |
| InParanoid | P52643 | |
| KO | K03778 | |
| OMA | LMMTLNR | |
| OrthoDB | EOG61VZ8G | |
| PhylomeDB | P52643 | |
| BioCyc | EcoCyc:DLACTDEHYDROGNAD-MONOMER ECOL316407:JW1375-MONOMER MetaCyc:DLACTDEHYDROGNAD-MONOMER | |
| PRO | PR:P52643 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P52643 | |
| GO | GO:0008720 GO:0070404 GO:0016616 GO:0019664 GO:0009408 | |
| Gene3D | 3.40.50.720 | |
| InterPro | IPR006139 IPR029753 IPR029752 IPR006140 IPR016040 | |
| Pfam | PF00389 PF02826 | |
| PROSITE | PS00065 PS00670 PS00671 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0008720 |
D-lactate dehydrogenase activity |
ECO:0000316 |
|
F |
Table 3. LDH Mutants of E. Coli and their LDH activity Figure 1. Wild type and mutant NMR of fermentation products |
complete | ||||
| GO:0019661 |
glucose catabolic process to lactate via pyruvate |
ECO:0000316 |
|
P |
Figure 1. NMR analysis of fermentation products |
complete | ||||
|
enables |
GO:0008720 |
D-lactate dehydrogenase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG13186 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0070404 |
NADH binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009408 |
response to heat |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009408 |
response to heat |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019664 |
mixed acid fermentation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019664 |
mixed acid fermentation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008720 |
D-lactate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051287 |
NAD binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008720 |
D-lactate dehydrogenase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Mat-Jan, F et al. (1989) Mutants of Escherichia coli deficient in the fermentative lactate dehydrogenase. J. Bacteriol. 171 342-8 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Tarmy, EM & Kaplan, NO (1968) Chemical characterization of D-lactate dehydrogenase from Escherichia coli B. J. Biol. Chem. 243 2579-86 PubMed GONUTS page
- ↑ Chuang, SE & Blattner, FR (1993) Characterization of twenty-six new heat shock genes of Escherichia coli. J. Bacteriol. 175 5242-52 PubMed GONUTS page
- ↑ Zhao, K et al. (2005) The global transcriptional response of Escherichia coli to induced sigma 32 protein involves sigma 32 regulon activation followed by inactivation and degradation of sigma 32 in vivo. J. Biol. Chem. 280 17758-68 PubMed GONUTS page
- ↑ Alam, KY & Clark, DP (1989) Anaerobic fermentation balance of Escherichia coli as observed by in vivo nuclear magnetic resonance spectroscopy. J. Bacteriol. 171 6213-7 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
