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ECOLI:HFLK
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | hflK (synonyms: hflA) | |
| Protein Name(s) | Modulator of FtsH protease HflK | |
| External Links | ||
| UniProt | P0ABC7 | |
| EMBL | U00005 U14003 U00096 AP009048 | |
| PIR | B43653 | |
| RefSeq | NP_418595.1 YP_492316.1 | |
| ProteinModelPortal | P0ABC7 | |
| SMR | P0ABC7 | |
| DIP | DIP-47481N | |
| IntAct | P0ABC7 | |
| MINT | MINT-1271770 | |
| STRING | 511145.b4174 | |
| MEROPS | I87.002 | |
| PaxDb | P0ABC7 | |
| PRIDE | P0ABC7 | |
| EnsemblBacteria | AAC77131 BAE78175 | |
| GeneID | 12932259 948698 | |
| KEGG | ecj:Y75_p4060 eco:b4174 | |
| PATRIC | 32123921 | |
| EchoBASE | EB0431 | |
| EcoGene | EG10436 | |
| eggNOG | COG0330 | |
| HOGENOM | HOG000260983 | |
| InParanoid | P0ABC7 | |
| KO | K04088 | |
| OMA | KAQEDEQ | |
| OrthoDB | EOG6J48MH | |
| PhylomeDB | P0ABC7 | |
| BioCyc | EcoCyc:EG10436-MONOMER ECOL316407:JW4132-MONOMER MetaCyc:EG10436-MONOMER | |
| PRO | PR:P0ABC7 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P0ABC7 | |
| GO | GO:0071575 GO:0048553 GO:0009408 | |
| InterPro | IPR001107 IPR010201 IPR020980 IPR001972 | |
| PANTHER | PTHR10264 PTHR10264:SF51 | |
| Pfam | PF01145 PF12221 | |
| PRINTS | PR00721 | |
| SMART | SM00244 | |
| TIGRFAMs | TIGR01933 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0006508 |
proteolysis |
ECO:0000314 |
P |
Knockout phenotypes demonstrated diminished proteolytic activity. |
complete | |||||
|
involved_in |
GO:0009408 |
response to heat |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0098796 |
membrane protein complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0071575 |
integral component of external side of plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0071575 |
integral component of external side of plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043086 |
negative regulation of catalytic activity |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-1003 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Bandyopadhyay, K et al. (2011) Studies on Escherichia coli HflKC suggest the presence of an unidentified λ factor that influences the lysis-lysogeny switch. BMC Microbiol. 11 34 PubMed GONUTS page
- ↑ Chuang, SE & Blattner, FR (1993) Characterization of twenty-six new heat shock genes of Escherichia coli. J. Bacteriol. 175 5242-52 PubMed GONUTS page
- ↑ 3.0 3.1 Kihara, A et al. (1996) A protease complex in the Escherichia coli plasma membrane: HflKC (HflA) forms a complex with FtsH (HflB), regulating its proteolytic activity against SecY. EMBO J. 15 6122-31 PubMed GONUTS page
- ↑ Kihara, A & Ito, K (1998) Translocation, folding, and stability of the HflKC complex with signal anchor topogenic sequences. J. Biol. Chem. 273 29770-5 PubMed GONUTS page
- ↑ Zorick, TS & Echols, H (1991) Membrane localization of the HflA regulatory protease of Escherichia coli by immunoelectron microscopy. J. Bacteriol. 173 6307-10 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
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