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ECOLI:END1

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) endA
Protein Name(s) Endonuclease-1

Endonuclease I Endo I

External Links
UniProt P25736
EMBL X65169
U28377
U00096
AP009048
PIR A38966
RefSeq NP_417420.1
WP_000286500.1
ProteinModelPortal P25736
SMR P25736
STRING 511145.b2945
EnsemblBacteria AAC75982
BAE77008
GeneID 949092
KEGG eco:b2945
PATRIC 32121300
EchoBASE EB1312
EcoGene EG11336
eggNOG COG2356
HOGENOM HOG000281182
InParanoid P25736
KO K01150
OMA ADQYGQC
OrthoDB EOG6DRPG6
PhylomeDB P25736
BioCyc EcoCyc:EG11336-MONOMER
ECOL316407:JW2912-MONOMER
MetaCyc:EG11336-MONOMER
PRO PR:P25736
Proteomes UP000000318
UP000000625
GO GO:0042597
GO:0004530
GO:0016888
GO:0004519
GO:0006308
GO:0090305
InterPro IPR007346
Pfam PF04231

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0016888

endodeoxyribonuclease activity, producing 5'-phosphomonoesters

PMID:14463751[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006308

DNA catabolic process

PMID:4105037[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004519

endonuclease activity

PMID:4991605[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004518

P

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004519

P

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004519

P

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004518

P

Seeded From UniProt

complete

enables

GO:0004518

nuclease activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007346

F

Seeded From UniProt

complete

enables

GO:0004530

deoxyribonuclease I activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.21.1

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

part_of

GO:0042597

periplasmic space

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0574
UniProtKB-SubCell:SL-0200

C

Seeded From UniProt

complete

enables

GO:0004518

nuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0540

F

Seeded From UniProt

complete

enables

GO:0004519

endonuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0255

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. LEHMAN, IR et al. (1962) The deoxyribonucleases of Escherichia coli. II. Purification and properties of a ribonucleic acid-inhibitable endonuclease. J. Biol. Chem. 237 819-28 PubMed GONUTS page
  2. Wright, M (1971) Mutants of Escherichia coli lacking endonuclease I, ribonuclease I, or ribonuclease II. J. Bacteriol. 107 87-94 PubMed GONUTS page
  3. Goebel, W & Helinski, DR (1970) Nicking activity of an endonuclease. I. Transfer ribonucleic acid complex of Escherichia coli. Biochemistry 9 4793-801 PubMed GONUTS page