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ECOLI:EMRA

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) emrA
Protein Name(s) Multidrug export protein EmrA
External Links
UniProt P27303
EMBL M86657
U00096
AP009048
PIR F65048
RefSeq NP_417170.1
YP_490899.1
ProteinModelPortal P27303
SMR P27303
DIP DIP-9502N
IntAct P27303
STRING 511145.b2685
TCDB 8.A.1.1.1
PaxDb P27303
PRIDE P27303
EnsemblBacteria AAC75732
BAA16547
GeneID 12933952
947166
KEGG ecj:Y75_p2628
eco:b2685
PATRIC 32120764
EchoBASE EB1329
EcoGene EG11354
eggNOG COG1566
HOGENOM HOG000112072
InParanoid P27303
KO K03543
OMA LLVLRHY
OrthoDB EOG6C014B
PhylomeDB P27303
BioCyc EcoCyc:EG11354-MONOMER
ECOL316407:JW2660-MONOMER
PRO PR:P27303
Proteomes UP000000318
UP000000625
Genevestigator P27303
GO GO:0009276
GO:0016021
GO:0031237
GO:0031226
GO:0015238
GO:0046677
InterPro IPR005694
IPR006143
Pfam PF00529
TIGRFAMs TIGR00998

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0042802

identical protein binding

PMID:24561554[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P27303

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:19805313[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P27303

F

Seeded From UniProt

complete

part_of

GO:0031226

intrinsic component of plasma membrane

PMID:1409590[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0031237

intrinsic component of periplasmic side of plasma membrane

PMID:12482849[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005215

transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006143

F

Seeded From UniProt

complete

involved_in

GO:0006855

drug transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005694

P

Seeded From UniProt

complete

enables

GO:0015238

drug transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005694

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006143

C

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006143

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-KW:KW-0997
UniProtKB-SubCell:SL-0037

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0046677

response to antibiotic

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0046

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Rajagopala, SV et al. (2014) The binary protein-protein interaction landscape of Escherichia coli. Nat. Biotechnol. 32 285-90 PubMed GONUTS page
  2. Tikhonova, EB et al. (2009) Kinetic control of TolC recruitment by multidrug efflux complexes. Proc. Natl. Acad. Sci. U.S.A. 106 16416-21 PubMed GONUTS page
  3. Lomovskaya, O & Lewis, K (1992) Emr, an Escherichia coli locus for multidrug resistance. Proc. Natl. Acad. Sci. U.S.A. 89 8938-42 PubMed GONUTS page
  4. Borges-Walmsley, MI et al. (2003) Identification of oligomerization and drug-binding domains of the membrane fusion protein EmrA. J. Biol. Chem. 278 12903-12 PubMed GONUTS page