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ECOLI:DPO3X
Contents
Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
Gene Name(s) | dnaX (synonyms: dnaZ, dnaZX) | |
Protein Name(s) | DNA polymerase III subunit tau
DNA polymerase III subunit gamma | |
External Links | ||
UniProt | P06710 | |
EMBL | X04487 X04487 X04275 U82664 U00096 AP009048 M38777 | |
PIR | A25549 | |
RefSeq | NP_415003.1 YP_488761.1 | |
PDB | 1JR3 1NJF 1NJG 1XXH 1XXI 2AYA 3GLF 3GLG 3GLH 3GLI | |
PDBsum | 1JR3 1NJF 1NJG 1XXH 1XXI 2AYA 3GLF 3GLG 3GLH 3GLI | |
ProteinModelPortal | P06710 | |
SMR | P06710 | |
DIP | DIP-9464N | |
IntAct | P06710 | |
MINT | MINT-1222776 | |
STRING | 511145.b0470 | |
BindingDB | P06710 | |
PaxDb | P06710 | |
PRIDE | P06710 | |
EnsemblBacteria | AAC73572 BAE76249 | |
GeneID | 12930852 945105 | |
KEGG | ecj:Y75_p0457 eco:b0470 | |
PATRIC | 32116097 | |
EchoBASE | EB0241 | |
EcoGene | EG10245 | |
eggNOG | COG2812 | |
HOGENOM | HOG000083934 | |
InParanoid | P06710 | |
KO | K02343 | |
OMA | AMGQGQV | |
OrthoDB | EOG6WQD76 | |
PhylomeDB | P06710 | |
BioCyc | EcoCyc:EG10245-MONOMER EcoCyc:MONOMER0-2383 ECOL316407:JW0459-MONOMER | |
EvolutionaryTrace | P06710 | |
PRO | PR:P06710 | |
Proteomes | UP000000318 UP000000625 | |
Genevestigator | P06710 | |
GO | GO:0043846 GO:0005524 GO:0016887 GO:0003677 GO:0030337 GO:0003887 GO:0042802 GO:0017111 GO:0006200 GO:0006260 | |
Gene3D | 3.40.50.300 | |
InterPro | IPR003593 IPR001270 IPR008921 IPR022001 IPR022754 IPR012763 IPR021029 IPR027417 | |
Pfam | PF12169 PF12168 PF12170 | |
PRINTS | PR00300 | |
SMART | SM00382 | |
SUPFAM | SSF48019 SSF52540 | |
TIGRFAMs | TIGR02397 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0006261 |
DNA-dependent DNA replication |
ECO:0000314 |
P |
Table 1 |
complete | |||||
involved_in |
GO:0006261 |
DNA-dependent DNA replication |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11500 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
occurs_in:(GO:0043846) |
Seeded From UniProt |
complete | ||
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
occurs_in:(GO:0043846) |
Seeded From UniProt |
complete | ||
part_of |
GO:0043846 |
DNA polymerase III, clamp loader complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0030337 |
DNA polymerase processivity factor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0030337 |
DNA polymerase processivity factor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0017111 |
nucleoside-triphosphatase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016887 |
ATPase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006260 |
DNA replication |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006259 |
DNA metabolic process |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0030337 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006259 |
DNA metabolic process |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0030337 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0071897 |
DNA biosynthetic process |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0003887 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0071897 |
DNA biosynthetic process |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0003887 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0071897 |
DNA biosynthetic process |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0003887 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006260 |
DNA replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0009360 |
DNA polymerase III complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006260 |
DNA replication |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016779 |
nucleotidyltransferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Wickner, S & Hurwitz, J (1974) Conversion of phiX174 viral DNA to double-stranded form by purified Escherichia coli proteins. Proc. Natl. Acad. Sci. U.S.A. 71 4120-4 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Rajagopala, SV et al. (2014) The binary protein-protein interaction landscape of Escherichia coli. Nat. Biotechnol. 32 285-90 PubMed GONUTS page
- ↑ Park, AY et al. (2010) A single subunit directs the assembly of the Escherichia coli DNA sliding clamp loader. Structure 18 285-92 PubMed GONUTS page
- ↑ 5.0 5.1 Glover, BP et al. (2001) tau binds and organizes Escherichia coli replication proteins through distinct domains: domain III, shared by gamma and tau, oligomerizes DnaX. J. Biol. Chem. 276 35842-6 PubMed GONUTS page
- ↑ Pritchard, AE et al. (2000) A novel assembly mechanism for the DNA polymerase III holoenzyme DnaX complex: association of deltadelta' with DnaX(4) forms DnaX(3)deltadelta'. EMBO J. 19 6536-45 PubMed GONUTS page
- ↑ Blinkova, A et al. (1993) The Escherichia coli DNA polymerase III holoenzyme contains both products of the dnaX gene, tau and gamma, but only tau is essential. J. Bacteriol. 175 6018-27 PubMed GONUTS page
- ↑ Olson, MW et al. (1995) DnaX complex of Escherichia coli DNA polymerase III holoenzyme. The chi psi complex functions by increasing the affinity of tau and gamma for delta.delta' to a physiologically relevant range. J. Biol. Chem. 270 29570-7 PubMed GONUTS page
- ↑ Jeruzalmi, D et al. (2001) Crystal structure of the processivity clamp loader gamma (gamma) complex of E. coli DNA polymerase III. Cell 106 429-41 PubMed GONUTS page
- ↑ Walker, JR et al. (2000) Escherichia coli DNA polymerase III tau- and gamma-subunit conserved residues required for activity in vivo and in vitro. J. Bacteriol. 182 6106-13 PubMed GONUTS page
- ↑ Tsuchihashi, Z & Kornberg, A (1989) ATP interactions of the tau and gamma subunits of DNA polymerase III holoenzyme of Escherichia coli. J. Biol. Chem. 264 17790-5 PubMed GONUTS page
- ↑ Henson, JM et al. (1979) Isolation and characterization of dnaX and dnaY temperature-sensitive mutants of Escherichia coli. Genetics 92 1041-59 PubMed GONUTS page
b
d
- GO:0003887 ! DNA-directed DNA polymerase activity
- GO:0006261 ! DNA-templated DNA replication
- GO:0003677 ! DNA binding
- GO:0071897 ! DNA biosynthetic process
- GO:0006259 ! DNA metabolic process
- GO:0030337 ! DNA polymerase processivity factor activity
- GO:0009360 ! DNA polymerase III complex
- GO:0043846 ! DNA polymerase III, clamp loader complex
- GO:0006260 ! DNA replication