ECOLI:DNAG

Species (Taxon ID)	Escherichia coli (strain K12). (83333)
Gene Name(s)	dnaG (ECO:0000255 with HAMAP-Rule:MF_00974) (synonyms: dnaP, parB)
Protein Name(s)	DNA primase (ECO:0000255 with HAMAP-Rule:MF_00974)
External Links
UniProt	P0ABS5
EMBL	J01687 V00274 U28379 U00096 AP009048 V00346
PIR	A03423
RefSeq	NP_417538.1 WP_000918827.1
PDB	1DD9 1DDE 1EQN 1T3W 2HAJ 3B39
PDBsum	1DD9 1DDE 1EQN 1T3W 2HAJ 3B39
ProteinModelPortal	P0ABS5
SMR	P0ABS5
BioGrid	4262146
DIP	DIP-47954N
IntAct	P0ABS5
MINT	MINT-1222307
STRING	511145.b3066
PaxDb	P0ABS5
PRIDE	P0ABS5
EnsemblBacteria	AAC76102 BAE77117
GeneID	947570
KEGG	ecj:JW3038 eco:b3066
PATRIC	32121546
EchoBASE	EB0235
EcoGene	EG10239
eggNOG	ENOG4105C9G COG0358
HOGENOM	HOG000014483
InParanoid	P0ABS5
KO	K02316
OMA	HDQLEFP
OrthoDB	EOG6XDGTR
PhylomeDB	P0ABS5
BioCyc	EcoCyc:EG10239-MONOMER ECOL316407:JW3038-MONOMER MetaCyc:EG10239-MONOMER
EvolutionaryTrace	P0ABS5
PRO	PR:P0ABS5
Proteomes	UP000000318 UP000000625
GO	GO:0005737 GO:1990077 GO:0003677 GO:0003896 GO:0000287 GO:0008270 GO:0006269
Gene3D	1.10.860.10 3.90.580.10 3.90.980.10
HAMAP	MF_00974
InterPro	IPR016136 IPR013264 IPR019475 IPR006295 IPR013173 IPR030846 IPR006171 IPR002694
Pfam	PF10410 PF08278 PF08275 PF01807
PIRSF	PIRSF002811
SMART	SM00766 SM00493 SM00400
TIGRFAMs	TIGR01391
PROSITE	PS50880

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
	GO:0006269	DNA replication, synthesis of RNA primer	PMID:16672615^[1]	ECO:0000315			P	Fig. 2	complete CACAO 8286
involved_in	GO:0006269	DNA replication, synthesis of RNA primer	PMID:16672615^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0006269	DNA replication, synthesis of RNA primer	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10239 PANTHER:PTN001250916	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10239 PANTHER:PTN001250916	C	Seeded From UniProt	complete
enables	GO:0003896	DNA primase activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10239 PANTHER:PTN001250916	F	Seeded From UniProt	complete
enables	GO:0008270	zinc ion binding	PMID:1511009^[3]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0006269	DNA replication, synthesis of RNA primer	PMID:340457^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:340457^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0003896	DNA primase activity	PMID:340457^[4]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002694 InterPro:IPR036977	F	Seeded From UniProt	complete
enables	GO:0003896	DNA primase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002694 InterPro:IPR006295 InterPro:IPR013173 InterPro:IPR030846	F	Seeded From UniProt	complete
involved_in	GO:0006260	DNA replication	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002694 InterPro:IPR036977	P	Seeded From UniProt	complete
involved_in	GO:0006269	DNA replication, synthesis of RNA primer	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006295 InterPro:IPR013173 InterPro:IPR030846	P	Seeded From UniProt	complete
enables	GO:0008270	zinc ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002694 InterPro:IPR030846 InterPro:IPR036977	F	Seeded From UniProt	complete
enables	GO:0016779	nucleotidyltransferase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR019475	F	Seeded From UniProt	complete
enables	GO:0003896	DNA primase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000113487	F	Seeded From UniProt	complete
enables	GO:0008270	zinc ion binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000113487	F	Seeded From UniProt	complete
involved_in	GO:0006269	DNA replication, synthesis of RNA primer	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000113487	P	Seeded From UniProt	complete
part_of	GO:1990077	primosome complex	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0639	C	Seeded From UniProt	complete
involved_in	GO:0006269	DNA replication, synthesis of RNA primer	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0639	P	Seeded From UniProt	complete
involved_in	GO:0006260	DNA replication	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0235	P	Seeded From UniProt	complete
enables	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0240	F	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
enables	GO:0016779	nucleotidyltransferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0548	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F	Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Rodina, A & Godson, GN (2006) Role of conserved amino acids in the catalytic activity of Escherichia coli primase. J. Bacteriol. 188 3614-21 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Stamford, NP et al. (1992) Enriched sources of Escherichia coli replication proteins. The dnaG primase is a zinc metalloprotein. Biochim. Biophys. Acta 1132 17-25 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 Rowen, L & Kornberg, A (1978) Primase, the dnaG protein of Escherichia coli. An enzyme which starts DNA chains. J. Biol. Chem. 253 758-64 PubMed GONUTS page

[PMID:16672615-1] 1.0 ^1.1 Rodina, A & Godson, GN (2006) Role of conserved amino acids in the catalytic activity of Escherichia coli primase. J. Bacteriol. 188 3614-21 PubMed GONUTS page

[PMID:21873635-2] 2.0 ^2.1 ^2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:1511009-3] Stamford, NP et al. (1992) Enriched sources of Escherichia coli replication proteins. The dnaG primase is a zinc metalloprotein. Biochim. Biophys. Acta 1132 17-25 PubMed GONUTS page

[PMID:340457-4] 4.0 ^4.1 ^4.2 Rowen, L & Kornberg, A (1978) Primase, the dnaG protein of Escherichia coli. An enzyme which starts DNA chains. J. Biol. Chem. 253 758-64 PubMed GONUTS page

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ECOLI:DNAG

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