ECODH:AAEA

Species (Taxon ID)	Escherichia coli (strain K12 / DH10B). (316385)
Gene Name(s)	aaeA (ECO:0000255 with HAMAP-Rule:MF_01544)
Protein Name(s)	p-hydroxybenzoic acid efflux pump subunit AaeA (ECO:0000255 with HAMAP-Rule:MF_01544) pHBA efflux pump protein A (ECO:0000255 with HAMAP-Rule:MF_01544)
External Links
UniProt	B1XHL3
EMBL	CP000948
RefSeq	WP_000854021.1
ProteinModelPortal	B1XHL3
SMR	B1XHL3
STRING	316385.ECDH10B_3418
EnsemblBacteria	ACB04314
KEGG	ecd:ECDH10B_3418
PATRIC	18466763
eggNOG	ENOG4105Y49 COG1566
HOGENOM	HOG000112073
KO	K15548
OMA	RRENKRN
OrthoDB	EOG6HXJ2X
BioCyc	ECOL316385:GJ8B-3274-MONOMER
GO	GO:0016021 GO:0005886 GO:0055085
HAMAP	MF_01544
InterPro	IPR022871 IPR006143
TIGRFAMs	TIGR01730

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0004514	NAD biosynthetic process	PMID:8561507	ECO:0000314			P		The nadC gene from Escherichia coli was isolated and sequenced. The gene was then cloned into an expression vector and, following transformation, the resulting bacteria were able to produce quinolinate phosphoribosyl transferase as about 2% of the soluble protein. The enzyme was purified in five steps leading to a homogeneous preparation. The enzyme reaction shows an ordered binding mechanism where the magnesium ion complex of 5-phosphoribosyl-1-pyrophosphate binds first followed by quinolinic acid. The products are pyrophosphate, CO2, and nicotinate mononucleotide.	complete CACAO 11675
enables	GO:0005215	transporter activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006143	F		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006143	C		Seeded From UniProt	complete
involved_in	GO:0055085	transmembrane transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006143	P		Seeded From UniProt	complete
enables	GO:0022857	transmembrane transporter activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000055597	F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000055597	C		Seeded From UniProt	complete
involved_in	GO:0055085	transmembrane transport	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000055597	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-KW:KW-0997 UniProtKB-SubCell:SL-0037	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
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References

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