EBVA8:BARF1

Species (Taxon ID)	Epstein-Barr virus (strain AG876) (HHV-4) (Human herpesvirus 4). (82830)
Gene Name(s)	BARF1
Protein Name(s)	Secreted protein BARF1 33 kDa early protein p33
External Links
UniProt	P0C6N0
EMBL	DQ279927
RefSeq	YP_001129512.1 YP_401719.1
ProteinModelPortal	P0C6N0
SMR	P0C6N0
GeneID	3783772 5176183
Proteomes	UP000007639
GO	GO:0005576 GO:0051781
Gene3D	2.60.40.10
InterPro	IPR007110 IPR013783
PROSITE	PS50835

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0051781	positive regulation of cell division	PMID:23458996	ECO:0000314			P		Figure 2A directly displays the results of BARF1-trasnfected HaCaT cell growth over 16 days in comparison to vector alone-transfected cells. BARF1 is a secreted protein that can be a powerful mitogen. In the graph shown in figure 2A, three BARF1-transfected cell cultures display more than a two-fold increase in cell division compared to vector-transfected and vector free cell cultures. Figure 2B displays the presence of the BARF1 fusion peptide of the protein in the BARF1-transfectant cells which is not present in vector-transfectant cells. This figure demonstrates the role BARF1 plays in positively regulating cell division.	complete CACAO 7429
involved_in	GO:0051781	positive regulation of cell division	PMID:23458996	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
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References

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