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DROME:TWF
Contents
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | twf | |
| Protein Name(s) | Twinfilin | |
| External Links | ||
| UniProt | Q9VFM9 | |
| EMBL | AJ430055 AE014297 AY069613 | |
| RefSeq | NP_650338.1 | |
| UniGene | Dm.2042 | |
| ProteinModelPortal | Q9VFM9 | |
| SMR | Q9VFM9 | |
| BioGrid | 66796 | |
| STRING | 7227.FBpp0082352 | |
| PaxDb | Q9VFM9 | |
| PRIDE | Q9VFM9 | |
| EnsemblMetazoa | FBtr0082891 | |
| GeneID | 41719 | |
| KEGG | dme:Dmel_CG3172 | |
| UCSC | CG3172-RA | |
| CTD | 41719 | |
| FlyBase | FBgn0038206 | |
| eggNOG | NOG263290 | |
| GeneTree | ENSGT00530000063868 | |
| InParanoid | Q9VFM9 | |
| KO | K08870 | |
| OMA | HATPELK | |
| OrthoDB | EOG79GT6W | |
| PhylomeDB | Q9VFM9 | |
| GenomeRNAi | 41719 | |
| NextBio | 825221 | |
| Proteomes | UP000000803 | |
| Bgee | Q9VFM9 | |
| GO | GO:0005938 GO:0005737 GO:0005856 GO:0005886 GO:0003779 GO:0030042 GO:0007298 GO:0008407 GO:0016319 GO:0030837 GO:0007274 GO:0030833 GO:0010591 GO:0048488 | |
| Gene3D | 3.40.20.10 | |
| InterPro | IPR002108 IPR029006 IPR028458 | |
| PANTHER | PTHR13759 | |
| Pfam | PF00241 | |
| SMART | SM00102 | |
| PROSITE | PS51263 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0030837 |
negative regulation of actin filament polymerization |
ECO:0000315 |
P |
Figure 3 & 4. |
complete | |||||
|
involved_in |
GO:0030837 |
negative regulation of actin filament polymerization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030833 |
regulation of actin filament polymerization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003779 |
actin binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051016 |
barbed-end actin filament capping |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1100520 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0051015 |
actin filament binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001011683 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042989 |
sequestering of actin monomers |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1100520 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030042 |
actin filament depolymerization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0038206 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0030016 |
myofibril |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1100520 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010976 |
positive regulation of neuron projection development |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001011684 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010591 |
regulation of lamellipodium assembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0038206 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005884 |
actin filament |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001011683 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0038206 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003785 |
actin monomer binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1100520 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0048488 |
synaptic vesicle endocytosis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007274 |
neuromuscular synaptic transmission |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007298 |
border follicle cell migration |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016319 |
mushroom body development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010591 |
regulation of lamellipodium assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008407 |
chaeta morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030042 |
actin filament depolymerization |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0098793 |
presynapse |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0048488 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003779 |
actin binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030837 |
negative regulation of actin filament polymerization |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003779 |
actin binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005938 |
cell cortex |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Wang, D et al. (2010) Drosophila twinfilin is required for cell migration and synaptic endocytosis. J. Cell. Sci. 123 1546-56 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Wahlström, G et al. (2001) Twinfilin is required for actin-dependent developmental processes in Drosophila. J. Cell Biol. 155 787-96 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 3.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Iwasa, JH & Mullins, RD (2007) Spatial and temporal relationships between actin-filament nucleation, capping, and disassembly. Curr. Biol. 17 395-406 PubMed GONUTS page
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