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PMID:17331727

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Citation

Iwasa, JH and Mullins, RD (2007) Spatial and temporal relationships between actin-filament nucleation, capping, and disassembly. Curr. Biol. 17:395-406

Abstract

The leading actin network in motile cells is composed of two compartments, the lamellipod and the lamellum. Construction of the lamellipod requires a set of conserved proteins that form a biochemical cycle. The timing of this cycle and the roles of its components in determining actin network architecture in vivo, however, are not well understood.

Links

PubMed PMC3077992 Online version:10.1016/j.cub.2007.02.012

Keywords

Actin Capping Proteins/genetics; Actin Capping Proteins/metabolism; Actin-Related Protein 2/genetics; Actin-Related Protein 2/metabolism; Actin-Related Protein 3/genetics; Actin-Related Protein 3/metabolism; Actins/genetics; Actins/metabolism; Animals; Cells, Cultured; Drosophila/cytology; Drosophila/metabolism; Green Fluorescent Proteins/genetics; Green Fluorescent Proteins/metabolism; Microscopy, Fluorescence; Pseudopodia/metabolism; Tropomyosin/genetics; Tropomyosin/metabolism

Significance

Annotations

Gene product Qualifier GO ID GO term name Evidence Code with/from Aspect Notes Status


See also

References

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