It is now the 1st OPEN Period for CACAO Fall 2017! It will end on Sunday September 24, 2017 at 11:59 pm CDT
This is your chance to make annotations OR challenge other team's annotations. You may also DEFEND or suggest improvements to your own annotations IF they have been challenged. Please note, although we ENCOURAGE challenges, an excess of identical challenges that do not appear to be applicable to the annotation or well thought out will be considered spam and ignored.

Have any questions? Please email us at ecoliwiki@gmail.com

DROME:Q9W0R8

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) No Information Provided.
Protein Name(s) Four wheel drive, isoform A (ECO:0000313 with EMBL:AAF47375.2)

Four wheel drive, isoform B (ECO:0000313 with EMBL:AAN11437.1) Four wheel drive, isoform D (ECO:0000313 with EMBL:AGB93898.1) LP07057p (ECO:0000313 with EMBL:AAK93473.1)

External Links
UniProt Q9W0R8
EMBL AE014296
AY052049
AE014296
AE014296
RefSeq NP_001261203.1
NP_524822.1
NP_728518.1
UniGene Dm.1632
EnsemblMetazoa FBtr0072515
FBtr0072516
FBtr0332841
GeneID 45374
KEGG dme:Dmel_CG7004
UCSC CG7004-RA
CTD 45374
FlyBase FBgn0004373
GeneTree ENSGT00550000074892
KO K00888
OMA GMMSARK
PhylomeDB Q9W0R8
Reactome REACT_180731
ChiTaRS fwd
GenomeRNAi 45374
NextBio 838086
PRO PR:Q9W0R8
Proteomes UP000000803
GO GO:0005737
GO:0004430
GO:0000916
GO:0008340
GO:0007030
GO:0030726
GO:0007112
GO:0007110
GO:0007111
GO:0043147
GO:0006661
GO:0048015
GO:0016310
GO:0090175
GO:0048137
GO:0007283
Gene3D 1.10.1070.11
InterPro IPR011009
IPR027003
IPR000403
IPR018936
IPR015433
PANTHER PTHR10048
PTHR10048:SF22
Pfam PF00454
SMART SM00146
SUPFAM SSF56112
PROSITE PS00915
PS00916
PS50290

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000916

actomyosin contractile ring contraction

PMID:15004238[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0004430

1-phosphatidylinositol 4-kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027003

F

Seeded From UniProt

complete

GO:0004430

1-phosphatidylinositol 4-kinase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.1.67

F

Seeded From UniProt

complete

GO:0004430

1-phosphatidylinositol 4-kinase activity

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000005893

F

Seeded From UniProt

complete

GO:0004430

1-phosphatidylinositol 4-kinase activity

PMID:10908587[2]

NAS: Non-traceable Author Statement

F

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000005673

C

Seeded From UniProt

complete

GO:0005794

Golgi apparatus

PMID:19995935[3]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0006661

phosphatidylinositol biosynthetic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027003

P

Seeded From UniProt

complete

GO:0007030

Golgi organization

PMID:24413170[4]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007110

meiosis I cytokinesis

PMID:15004238[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007111

meiosis II cytokinesis

PMID:15004238[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007112

male meiosis cytokinesis

PMID:10934029[5]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007112

male meiosis cytokinesis

PMID:17914057[6]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007112

male meiosis cytokinesis

PMID:19995935[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007283

spermatogenesis

PMID:19995935[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0008340

determination of adult lifespan

PMID:12620118[7]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0016020

membrane

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000005673

C

Seeded From UniProt

complete

GO:0016301

kinase activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

GO:0016310

phosphorylation

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

GO:0016310

phosphorylation

PMID:10908587[2]

NAS: Non-traceable Author Statement

P

Seeded From UniProt

complete

GO:0016740

transferase activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

GO:0016773

phosphotransferase activity, alcohol group as acceptor

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000403
InterPro:IPR018936

F

Seeded From UniProt

complete

GO:0030726

male germline ring canal formation

PMID:10934029[5]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0043147

meiotic spindle stabilization

PMID:15004238[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0046854

phosphatidylinositol phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015433

P

Seeded From UniProt

complete

GO:0046854

phosphatidylinositol phosphorylation

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000005673

P

Seeded From UniProt

complete

GO:0048015

phosphatidylinositol-mediated signaling

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015433

P

Seeded From UniProt

complete

GO:0048015

phosphatidylinositol-mediated signaling

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000005673

P

Seeded From UniProt

complete

GO:0048137

spermatocyte division

PMID:17914057[6]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0090175

regulation of establishment of planar polarity

PMID:22391484[8]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Giansanti, MG et al. (2004) Genetic dissection of meiotic cytokinesis in Drosophila males. Mol. Biol. Cell 15 2509-22 PubMed GONUTS page
  2. 2.0 2.1 Morrison, DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J. Cell Biol. 150 F57-62 PubMed GONUTS page
  3. 3.0 3.1 3.2 Polevoy, G et al. (2009) Dual roles for the Drosophila PI 4-kinase four wheel drive in localizing Rab11 during cytokinesis. J. Cell Biol. 187 847-58 PubMed GONUTS page
  4. Tan, J et al. (2014) PI4KIIIα is required for cortical integrity and cell polarity during Drosophila oogenesis. J. Cell. Sci. 127 954-66 PubMed GONUTS page
  5. 5.0 5.1 Brill, JA et al. (2000) A phospholipid kinase regulates actin organization and intercellular bridge formation during germline cytokinesis. Development 127 3855-64 PubMed GONUTS page
  6. 6.0 6.1 Giansanti, MG et al. (2007) Rab11 is required for membrane trafficking and actomyosin ring constriction in meiotic cytokinesis of Drosophila males. Mol. Biol. Cell 18 5034-47 PubMed GONUTS page
  7. Landis, GN et al. (2003) A search for doxycycline-dependent mutations that increase Drosophila melanogaster life span identifies the VhaSFD, Sugar baby, filamin, fwd and Cctl genes. Genome Biol. 4 R8 PubMed GONUTS page
  8. Weber, U et al. (2012) Novel regulators of planar cell polarity: a genetic analysis in Drosophila. Genetics 191 145-62 PubMed GONUTS page