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DROME:Q9W0R8

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) No Information Provided.
Protein Name(s) Four wheel drive, isoform A (ECO:0000313 with EMBL:AAF47375.2)

Four wheel drive, isoform B (ECO:0000313 with EMBL:AAN11437.1) Four wheel drive, isoform D (ECO:0000313 with EMBL:AGB93898.1) LP07057p (ECO:0000313 with EMBL:AAK93473.1)

External Links
UniProt Q9W0R8
EMBL AE014296
AY052049
AE014296
AE014296
RefSeq NP_001261203.1
NP_524822.1
NP_728518.1
UniGene Dm.1632
EnsemblMetazoa FBtr0072515
FBtr0072516
FBtr0332841
GeneID 45374
KEGG dme:Dmel_CG7004
UCSC CG7004-RA
CTD 45374
FlyBase FBgn0004373
GeneTree ENSGT00550000074892
KO K00888
OMA GMMSARK
PhylomeDB Q9W0R8
Reactome REACT_180731
ChiTaRS fwd
GenomeRNAi 45374
NextBio 838086
PRO PR:Q9W0R8
Proteomes UP000000803
GO GO:0005737
GO:0004430
GO:0000916
GO:0008340
GO:0007030
GO:0030726
GO:0007112
GO:0007110
GO:0007111
GO:0043147
GO:0006661
GO:0048015
GO:0016310
GO:0090175
GO:0048137
GO:0007283
Gene3D 1.10.1070.11
InterPro IPR011009
IPR027003
IPR000403
IPR018936
IPR015433
PANTHER PTHR10048
PTHR10048:SF22
Pfam PF00454
SMART SM00146
SUPFAM SSF56112
PROSITE PS00915
PS00916
PS50290

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0048015

phosphatidylinositol-mediated signaling

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000005673
RGD:620899
dictyBase:DDB_G0278727
dictyBase:DDB_G0283081

P

Seeded From UniProt

complete

involved_in

GO:0046854

phosphatidylinositol phosphorylation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0015277
FB:FBgn0015278
FB:FBgn0015279
FB:FBgn0267350
MGI:MGI:2448506
PANTHER:PTN000005673
RGD:620916
RGD:620917
SGD:S000004230
SGD:S000004296
SGD:S000005211
UniProtKB:A0A1D8PDV7
UniProtKB:P32871

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000005673
PomBase:SPAC458.05
TAIR:locus:2164401
UniProtKB:P48736

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000005673
RGD:621214
UniProtKB:O00443
UniProtKB:P42356
UniProtKB:P48736
WB:WBGene00000090
WB:WBGene00006932
WB:WBGene00009552
dictyBase:DDB_G0291093

C

Seeded From UniProt

complete

enables

GO:0004430

1-phosphatidylinositol 4-kinase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000005893
RGD:621214
SGD:S000005211
TAIR:locus:2164401
UniProtKB:Q57WD8
UniProtKB:Q580E2
UniProtKB:Q8I406
UniProtKB:Q9UBF8

F

Seeded From UniProt

complete

enables

GO:0004430

1-phosphatidylinositol 4-kinase activity

PMID:10908587[2]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

PMID:10908587[2]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0030726

male germline ring canal formation

PMID:10934029[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007112

male meiosis cytokinesis

PMID:10934029[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0000916

actomyosin contractile ring contraction

PMID:15004238[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0008340

determination of adult lifespan

PMID:12620118[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007030

Golgi organization

PMID:24413170[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0090175

regulation of establishment of planar polarity

PMID:22391484[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007283

spermatogenesis

PMID:19995935[8]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007112

male meiosis cytokinesis

PMID:19995935[8]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

PMID:19995935[8]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0048137

spermatocyte division

PMID:17914057[9]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007112

male meiosis cytokinesis

PMID:17914057[9]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007111

meiosis II cytokinesis

PMID:15004238[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007110

meiosis I cytokinesis

PMID:15004238[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0000212

meiotic spindle organization

PMID:15004238[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR018936
InterPro:IPR036940

F

Seeded From UniProt

complete

involved_in

GO:0046854

phosphatidylinositol phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015433

P

Seeded From UniProt

complete

involved_in

GO:0048015

phosphatidylinositol-mediated signaling

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015433

P

Seeded From UniProt

complete

enables

GO:0004430

1-phosphatidylinositol 4-kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.1.67

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000415644

F

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000415644

F

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. ↑ 2.0 2.1 Morrison, DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J. Cell Biol. 150 F57-62 PubMed GONUTS page
  3. ↑ 3.0 3.1 Brill, JA et al. (2000) A phospholipid kinase regulates actin organization and intercellular bridge formation during germline cytokinesis. Development 127 3855-64 PubMed GONUTS page
  4. ↑ 4.0 4.1 4.2 4.3 Giansanti, MG et al. (2004) Genetic dissection of meiotic cytokinesis in Drosophila males. Mol. Biol. Cell 15 2509-22 PubMed GONUTS page
  5. ↑ Landis, GN et al. (2003) A search for doxycycline-dependent mutations that increase Drosophila melanogaster life span identifies the VhaSFD, Sugar baby, filamin, fwd and Cctl genes. Genome Biol. 4 R8 PubMed GONUTS page
  6. ↑ Tan, J et al. (2014) PI4KIIIα is required for cortical integrity and cell polarity during Drosophila oogenesis. J. Cell. Sci. 127 954-66 PubMed GONUTS page
  7. ↑ Weber, U et al. (2012) Novel regulators of planar cell polarity: a genetic analysis in Drosophila. Genetics 191 145-62 PubMed GONUTS page
  8. ↑ 8.0 8.1 8.2 Polevoy, G et al. (2009) Dual roles for the Drosophila PI 4-kinase four wheel drive in localizing Rab11 during cytokinesis. J. Cell Biol. 187 847-58 PubMed GONUTS page
  9. ↑ 9.0 9.1 Giansanti, MG et al. (2007) Rab11 is required for membrane trafficking and actomyosin ring constriction in meiotic cytokinesis of Drosophila males. Mol. Biol. Cell 18 5034-47 PubMed GONUTS page
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