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DROME:Q9VSS1

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) No Information Provided.
Protein Name(s) Pixie, isoform A (ECO:0000313 with EMBL:AAF50342.1)

Pixie, isoform B (ECO:0000313 with EMBL:AAN11979.1) RE71924p (ECO:0000313 with EMBL:AAL90382.1)

External Links
UniProt Q9VSS1
EMBL AE014296
AY089644
AE014296
RefSeq NP_648272.1
NP_729435.1
UniGene Dm.7778
SMR Q9VSS1
IntAct Q9VSS1
MINT MINT-930375
STRING 7227.FBpp0076285
EnsemblMetazoa FBtr0076557
FBtr0076558
GeneID 39027
KEGG dme:Dmel_CG5651
UCSC CG5651-RA
CTD 39027
FlyBase FBgn0086706
eggNOG COG1245
GeneTree ENSGT00390000015089
KO K06174
OMA ISYKPQY
OrthoDB EOG70GMF4
PhylomeDB Q9VSS1
ChiTaRS pix
GenomeRNAi 39027
NextBio 811539
PRO PR:Q9VSS1
Proteomes UP000000803
GO GO:0005737
GO:0005524
GO:0016887
GO:0051536
GO:0043024
GO:0031369
GO:0016049
GO:0043524
GO:0006412
GO:0006413
Gene3D 3.40.50.300
InterPro IPR001450
IPR017896
IPR017900
IPR003593
IPR003439
IPR017871
IPR013283
IPR027417
IPR007209
PANTHER PTHR19248
Pfam PF00005
PF00037
PF04068
PRINTS PR01868
SMART SM00382
SUPFAM SSF52540
PROSITE PS00198
PS51379
PS00211
PS50893

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:17392269[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9VCK0

F

Seeded From UniProt

complete

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003439
InterPro:IPR017871

F

Seeded From UniProt

complete

GO:0005524

ATP binding

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

GO:0005524

ATP binding

PMID:17392269[1]

IMP: Inferred from Mutant Phenotype

F

Seeded From UniProt

complete

GO:0005737

cytoplasm

PMID:16291791[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

PMID:17392269[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0006412

translation

PMID:16291791[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0006413

translational initiation

PMID:17392269[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0016049

cell growth

PMID:16291791[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0016787

hydrolase activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

GO:0016887

ATPase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003439
InterPro:IPR017871

F

Seeded From UniProt

complete

GO:0016887

ATPase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:3.6.1.3

F

Seeded From UniProt

complete

GO:0031369

translation initiation factor binding

PMID:17392269[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q0E940

F

Seeded From UniProt

complete

GO:0031369

translation initiation factor binding

PMID:17392269[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q7K550

F

Seeded From UniProt

complete

GO:0043024

ribosomal small subunit binding

PMID:17392269[1]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0043524

negative regulation of neuron apoptotic process

PMID:16291791[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0051536

iron-sulfur cluster binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001450
InterPro:IPR017896

F

Seeded From UniProt

complete

GO:0070481

nuclear-transcribed mRNA catabolic process, non-stop decay

PMID:25128630[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

colocalizes_with

GO:0005852

eukaryotic translation initiation factor 3 complex

PMID:17392269[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Andersen, DS & Leevers, SJ (2007) The essential Drosophila ATP-binding cassette domain protein, pixie, binds the 40 S ribosome in an ATP-dependent manner and is required for translation initiation. J. Biol. Chem. 282 14752-60 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Coelho, CM et al. (2005) Growth and cell survival are unevenly impaired in pixie mutant wing discs. Development 132 5411-24 PubMed GONUTS page
  3. Kashima, I et al. (2014) A functional involvement of ABCE1, eukaryotic ribosome recycling factor, in nonstop mRNA decay in Drosophila melanogaster cells. Biochimie 106 10-6 PubMed GONUTS page