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DROME:Q9U4J0

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) ETH (ECO:0000313 with FlyBase:FBgn0028738)
Protein Name(s) Ecdysis-triggering hormone (ECO:0000313 with EMBL:AAF14282.1)
External Links
UniProt Q9U4J0
EMBL AF170922
STRING 7227.FBpp0072331
PRIDE Q9U4J0
FlyBase FBgn0028738
eggNOG NOG119055
OrthoDB EOG7V7684
ChiTaRS Crc
crc
Bgee Q9U4J0
GO GO:0005615
GO:0008255
GO:0001664
GO:0005184
GO:0005102
GO:0018990
GO:0007218

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005615

extracellular space

GO_REF:0000050

ECO:0000255

match to sequence model evidence used in manual assertion

C

Seeded From UniProt

Missing: with/from

involved_in

GO:0007218

neuropeptide signaling pathway

PMID:16441518[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:16441518[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0001664

G protein-coupled receptor binding

PMID:12586820[2]

ECO:0000353

physical interaction evidence used in manual assertion

FB:FBgn0038874

F

Seeded From UniProt

complete

enables

GO:0005102

signaling receptor binding

PMID:12177421[3]

ECO:0000250

sequence similarity evidence used in manual assertion

F

Seeded From UniProt

Missing: with/from

involved_in

GO:0018990

ecdysis, chitin-based cuticle

PMID:11807040[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008255

ecdysis-triggering hormone activity

PMID:11381038[5]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008255

ecdysis-triggering hormone activity

PMID:10601653[6]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0018990

ecdysis, chitin-based cuticle

PMID:10601653[6]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:10601653[6]

ECO:0000305

curator inference used in manual assertion

GO:0008255

C

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008255

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005184

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008255

P

Seeded From UniProt

complete

enables

GO:0005184

neuropeptide hormone activity

PMID:11179818[7]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0007218

neuropeptide signaling pathway

PMID:11179818[7]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Wegener, C et al. (2006) Direct mass spectrometric peptide profiling and fragmentation of larval peptide hormone release sites in Drosophila melanogaster reveals tagma-specific peptide expression and differential processing. J. Neurochem. 96 1362-74 PubMed GONUTS page
  2. Park, Y et al. (2003) Two subtypes of ecdysis-triggering hormone receptor in Drosophila melanogaster. J. Biol. Chem. 278 17710-5 PubMed GONUTS page
  3. Park, Y et al. (2002) Identification of G protein-coupled receptors for Drosophila PRXamide peptides, CCAP, corazonin, and AKH supports a theory of ligand-receptor coevolution. Proc. Natl. Acad. Sci. U.S.A. 99 11423-8 PubMed GONUTS page
  4. Park, Y et al. (2002) Deletion of the ecdysis-triggering hormone gene leads to lethal ecdysis deficiency. Development 129 493-503 PubMed GONUTS page
  5. Hewes, RS & Taghert, PH (2001) Neuropeptides and neuropeptide receptors in the Drosophila melanogaster genome. Genome Res. 11 1126-42 PubMed GONUTS page
  6. 6.0 6.1 6.2 Park, Y et al. (1999) Molecular cloning and biological activity of ecdysis-triggering hormones in Drosophila melanogaster. FEBS Lett. 463 133-8 PubMed GONUTS page
  7. 7.0 7.1 Vanden Broeck, J (2001) Neuropeptides and their precursors in the fruitfly, Drosophila melanogaster. Peptides 22 241-54 PubMed GONUTS page