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DROME:O96620

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) No Information Provided.
Protein Name(s) Intermediate neuroblasts defective protein (ECO:0000313 with EMBL:AAC97116.1)
External Links
UniProt O96620
EMBL AF095926
ProteinModelPortal O96620
SMR O96620
PRIDE O96620
FlyBase FBgn0025776
eggNOG NOG264927
OrthoDB EOG7C5M93
Bgee O96620
ExpressionAtlas O96620
GO GO:0005634
GO:0043565
GO:0003700
GO:0008134
GO:0007420
GO:0007417
GO:0009953
GO:0007398
GO:0010629
GO:0000122
GO:0007400
GO:0007389
GO:0006357
GO:0007419
Gene3D 1.10.10.60
InterPro IPR017970
IPR001356
IPR020479
IPR009057
Pfam PF00046
PRINTS PR00024
SMART SM00389
SUPFAM SSF46689
PROSITE PS00027
PS50071

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0007419

ventral cord development

PMID:26092715[1]

ECO:0007001

high throughput mutant phenotypic evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010629

negative regulation of gene expression

PMID:20673828[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

PMID:17360441[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:17360441[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

PMID:17360441[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008134

transcription factor binding

PMID:17360441[3]

ECO:0000353

physical interaction evidence used in manual assertion

FB:FBgn0000411

F

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

PMID:17360441[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007389

pattern specification process

PMID:15266339[4]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007417

central nervous system development

PMID:15266339[4]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007419

ventral cord development

PMID:12027434[5]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010629

negative regulation of gene expression

PMID:9832510[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:9832510[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0007417

central nervous system development

PMID:9832510[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001356
InterPro:IPR009057
InterPro:IPR020479

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017970

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017970

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0371

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000401037

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000401037

F

Seeded From UniProt

complete

involved_in

GO:0009953

dorsal/ventral pattern formation

PMID:15221856[7]
PMID:12593977[8]

ECO:0000304

author statement supported by traceable reference used in manual assertion


P

Seeded From UniProt

complete

involved_in

GO:0007420

brain development

PMID:15221856[7]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007398

ectoderm development

PMID:15221856[7]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007400

neuroblast fate determination

PMID:12593977[8]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007419

ventral cord development

PMID:12593977[8]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Bivik, C et al. (2015) Novel Genes Involved in Controlling Specification of Drosophila FMRFamide Neuropeptide Cells. Genetics 200 1229-44 PubMed GONUTS page
  2. Seibert, J & Urbach, R (2010) Role of en and novel interactions between msh, ind, and vnd in dorsoventral patterning of the Drosophila brain and ventral nerve cord. Dev. Biol. 346 332-45 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Zhao, G et al. (2007) Linking pattern formation to cell-type specification: Dichaete and Ind directly repress achaete gene expression in the Drosophila CNS. Proc. Natl. Acad. Sci. U.S.A. 104 3847-52 PubMed GONUTS page
  4. 4.0 4.1 Ball, EE et al. (2004) A simple plan--cnidarians and the origins of developmental mechanisms. Nat. Rev. Genet. 5 567-77 PubMed GONUTS page
  5. Stathopoulos, A & Levine, M (2002) Dorsal gradient networks in the Drosophila embryo. Dev. Biol. 246 57-67 PubMed GONUTS page
  6. 6.0 6.1 6.2 Weiss, JB et al. (1998) Dorsoventral patterning in the Drosophila central nervous system: the intermediate neuroblasts defective homeobox gene specifies intermediate column identity. Genes Dev. 12 3591-602 PubMed GONUTS page
  7. 7.0 7.1 7.2 Urbach, R & Technau, GM (2004) Neuroblast formation and patterning during early brain development in Drosophila. Bioessays 26 739-51 PubMed GONUTS page
  8. 8.0 8.1 8.2 Skeath, JB & Thor, S (2003) Genetic control of Drosophila nerve cord development. Curr. Opin. Neurobiol. 13 8-15 PubMed GONUTS page