GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
DROME:NGLY1
Contents
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | Pngl (synonyms: PNGase) | |
| Protein Name(s) | Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase
Peptide:N-glycanase | |
| External Links | ||
| UniProt | Q7KRR5 | |
| EMBL | AF250926 AE013599 AE013599 AY119239 BT001557 | |
| RefSeq | NP_610192.1 NP_724444.3 | |
| UniGene | Dm.3262 | |
| ProteinModelPortal | Q7KRR5 | |
| SMR | Q7KRR5 | |
| BioGrid | 61433 | |
| IntAct | Q7KRR5 | |
| MINT | MINT-881702 | |
| PaxDb | Q7KRR5 | |
| PRIDE | Q7KRR5 | |
| EnsemblMetazoa | FBtr0085972 | |
| GeneID | 35527 | |
| KEGG | dme:Dmel_CG7865 | |
| UCSC | CG7865-RA | |
| CTD | 35527 | |
| FlyBase | FBgn0033050 | |
| eggNOG | NOG307426 | |
| GeneTree | ENSGT00390000006540 | |
| InParanoid | Q7KRR5 | |
| KO | K01456 | |
| OMA | CQNTPET | |
| OrthoDB | EOG780RMR | |
| PhylomeDB | Q7KRR5 | |
| GenomeRNAi | 35527 | |
| NextBio | 793864 | |
| PRO | PR:Q7KRR5 | |
| Proteomes | UP000000803 | |
| Bgee | Q7KRR5 | |
| GO | GO:0005737 GO:0005829 GO:0030246 GO:0016787 GO:0046872 GO:0006516 | |
| InterPro | IPR008979 IPR006588 IPR018997 IPR006567 IPR002931 | |
| Pfam | PF09409 PF01841 | |
| SMART | SM00613 SM00580 SM00460 | |
| SUPFAM | SSF49785 | |
| PROSITE | PS51398 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0006516 |
glycoprotein catabolic process |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006517 |
protein deglycosylation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0033050 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006516 |
glycoprotein catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1913276 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006515 |
protein quality control for misfolded or incompletely synthesized proteins |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000254236 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0033050 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000254236 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000224 |
peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0033050 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030513 |
positive regulation of BMP signaling pathway |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007495 |
visceral mesoderm-endoderm interaction involved in midgut development |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
FB:FBgn0003716 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007495 |
visceral mesoderm-endoderm interaction involved in midgut development |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
FB:FBgn0000490 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006517 |
protein deglycosylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006517 |
protein deglycosylation |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000224 |
peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030246 |
carbohydrate binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
NOT|enables |
GO:0000224 |
peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006516 |
glycoprotein catabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Galeone, A et al. (2017) Tissue-specific regulation of BMP signaling by -glycanase 1. Elife 6 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Funakoshi, Y et al. (2010) Evidence for an essential deglycosylation-independent activity of PNGase in Drosophila melanogaster. PLoS ONE 5 e10545 PubMed GONUTS page
