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DROME:FDL

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) fdl
Protein Name(s) Probable beta-hexosaminidase fdl

Protein fused lobes

External Links
UniProt Q8WSF3
EMBL AF323977
AE013599
AE013599
AY113418
AY061037
RefSeq NP_001286350.1
NP_725178.2
NP_725179.1
UniGene Dm.3735
ProteinModelPortal Q8WSF3
SMR Q8WSF3
BioGrid 75345
DIP DIP-21467N
MINT MINT-1665363
STRING 7227.FBpp0087058
CAZy GH20
PaxDb Q8WSF3
PRIDE Q8WSF3
EnsemblMetazoa FBtr0087946
GeneID 250735
KEGG dme:Dmel_CG8824
CTD 250735
FlyBase FBgn0045063
eggNOG COG3525
GeneTree ENSGT00390000008107
InParanoid Q8WSF3
KO K12373
OMA VYKHRPW
OrthoDB EOG79W94H
PhylomeDB Q8WSF3
Reactome REACT_180740
REACT_180747
REACT_180778
REACT_212275
ChiTaRS fdl
GenomeRNAi 250735
NextBio 843498
Proteomes UP000000803
Bgee Q8WSF3
ExpressionAtlas Q8WSF3
GO GO:0005770
GO:0005886
GO:0016231
GO:0004563
GO:0007420
GO:0006491
Gene3D 3.20.20.80
3.30.379.10
InterPro IPR025705
IPR029018
IPR015883
IPR013781
IPR017853
IPR029019
Pfam PF00728
PF14845
PIRSF PIRSF001093
PRINTS PR00738
SUPFAM SSF51445
SSF55545

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0007420

brain development

PMID:10623899[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004563

beta-N-acetylhexosaminidase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P49010

F

Seeded From UniProt

complete

enables

GO:0008375

acetylglucosaminyltransferase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P06865

F

Seeded From UniProt

complete

involved_in

GO:0006491

N-glycan processing

PMID:24785692[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0016063

rhodopsin biosynthetic process

PMID:24785692[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006517

protein deglycosylation

PMID:24785692[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:16733265[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

colocalizes_with

GO:0005794

Golgi apparatus

PMID:16339150[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

colocalizes_with

GO:0005783

endoplasmic reticulum

PMID:16339150[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:16339150[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

NOT|involved_in

GO:0006032

chitin catabolic process

PMID:16339150[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0016231

beta-N-acetylglucosaminidase activity

PMID:16339150[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

NOT|enables

GO:0032428

beta-N-acetylgalactosaminidase activity

PMID:16339150[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005770

late endosome

PMID:16339150[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006491

N-glycan processing

PMID:16339150[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007420

brain development

PMID:10623899[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004553

hydrolase activity, hydrolyzing O-glycosyl compounds

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015883

F

Seeded From UniProt

complete

enables

GO:0004563

beta-N-acetylhexosaminidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR025705

F

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015883
InterPro:IPR025705

P

Seeded From UniProt

complete

enables

GO:0102148

N-acetyl-beta-D-galactosaminidase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.2.1.52

F

Seeded From UniProt

complete

enables

GO:0004563

beta-N-acetylhexosaminidase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.2.1.52

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0016798

hydrolase activity, acting on glycosyl bonds

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0326

F

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

involved_in

GO:0008152

metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0326

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Boquet, I et al. (2000) Central brain postembryonic development in Drosophila: implication of genes expressed at the interhemispheric junction. J. Neurobiol. 42 33-48 PubMed GONUTS page
  2. 2.0 2.1 2.2 Rosenbaum, EE et al. (2014) Mutations in four glycosyl hydrolases reveal a highly coordinated pathway for rhodopsin biosynthesis and N-glycan trimming in Drosophila melanogaster. PLoS Genet. 10 e1004349 PubMed GONUTS page
  3. Cattaneo, F et al. (2006) Identification and expression analysis of Drosophila melanogaster genes encoding beta-hexosaminidases of the sperm plasma membrane. Glycobiology 16 786-800 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 Léonard, R et al. (2006) The Drosophila fused lobes gene encodes an N-acetylglucosaminidase involved in N-glycan processing. J. Biol. Chem. 281 4867-75 PubMed GONUTS page