DROME:DYRK2

Species (Taxon ID)	Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s)	smi35A (synonyms: Dyrk2)
Protein Name(s)	Dual specificity tyrosine-phosphorylation-regulated kinase 2 Protein smell impaired at 35A dDyrk2
External Links
UniProt	Q9V3D5
EMBL	AF168467 AE014134 AE014134 AE014134 AE014134 AE014134 BT010088 AY069183
RefSeq	NP_001033906.1 NP_001033907.1 NP_523564.1 NP_995710.1 NP_995711.1
UniGene	Dm.2597
ProteinModelPortal	Q9V3D5
SMR	Q9V3D5
IntAct	Q9V3D5
PRIDE	Q9V3D5
EnsemblMetazoa	FBtr0089288 FBtr0089289 FBtr0089290 FBtr0100447 FBtr0100448
GeneID	34831
KEGG	dme:Dmel_CG4551
CTD	8445
FlyBase	FBgn0016930
eggNOG	COG0515
GeneTree	ENSGT00760000119032
InParanoid	Q9V3D5
KO	K18669
OrthoDB	EOG77127N
PhylomeDB	Q9V3D5
SignaLink	Q9V3D5
ChiTaRS	smi35A
GenomeRNAi	34831
NextBio	790436
PRO	PR:Q9V3D5
Proteomes	UP000000803
Bgee	Q9V3D5
ExpressionAtlas	Q9V3D5
GO	GO:0005829 GO:0005524 GO:0004672 GO:0004674 GO:0004712 GO:0004713 GO:0016740 GO:0042048 GO:0006468 GO:0009416 GO:0007608
InterPro	IPR011009 IPR000719 IPR017441 IPR002290 IPR008271
Pfam	PF00069
SMART	SM00220
SUPFAM	SSF56112
PROSITE	PS00107 PS50011 PS00108

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0042048	olfactory behavior	PMID:24146926	ECO:0000315			P		Figure 2 shows a t-maze assay using 1% benzaldehyde. Aversion was calculated with a response index and both mutant male and female DmDyrk2−/− mutants showed significantly less aversion to benzaldehyde.	complete CACAO 8965
enables	GO:0016740	transferase activity	PMID:12786602	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	PMID:12786602	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:12786602	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	PMID:12786602	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004674	protein serine/threonine kinase activity	PMID:12786602	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0007608	sensory perception of smell	PMID:24146926	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0009416	response to light stimulus	PMID:24146926	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	PMID:10908587	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0004672	protein kinase activity	PMID:10908587	ECO:0000303	author statement without traceable support used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0042048	olfactory behavior	PMID:8722782	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030177	positive regulation of Wnt signaling pathway	PMID:23583758	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0018108	peptidyl-tyrosine phosphorylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004713	P		Seeded From UniProt	complete
enables	GO:0004672	protein kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR008271	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR017441	F		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR008271	P		Seeded From UniProt	complete
enables	GO:0004712	protein serine/threonine/tyrosine kinase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.12.1	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
enables	GO:0016301	kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	F		Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	P		Seeded From UniProt	complete
enables	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0723	F		Seeded From UniProt	complete
enables	GO:0004713	protein tyrosine kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0829	F		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
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References

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