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DICDI:TOR

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Species (Taxon ID) Dictyostelium discoideum (Slime mold). (44689)
Gene Name(s) tor
Protein Name(s) Target of rapamycin
External Links
UniProt Q86C65
EMBL AY204354
AAFI02000042
RefSeq XP_640629.1
ProteinModelPortal Q86C65
STRING 44689.DDB0214908
PRIDE Q86C65
EnsemblProtists DDB0214908
EAL66546
GeneID 8623240
KEGG ddi:DDB_G0281569
dictyBase DDB_G0281569
eggNOG COG5032
InParanoid Q86C65
KO K07203
OMA PAMEPHI
PhylomeDB Q86C65
PRO PR:Q86C65
Proteomes UP000002195
UP000002195
GO GO:0031932
GO:0005524
GO:0008144
GO:0016301
GO:0004674
GO:0007049
GO:0006935
GO:0000724
Gene3D 1.10.1070.11
1.25.10.10
InterPro IPR011989
IPR016024
IPR024585
IPR003152
IPR021133
IPR011009
IPR000403
IPR018936
IPR003151
IPR014009
IPR009076
Pfam PF11865
PF02259
PF02260
PF00454
PF08771
SMART SM00146
SUPFAM SSF47212
SSF48371
SSF56112
PROSITE PS51189
PS51190
PS50077
PS00915
PS00916
PS50290

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005886

plasma membrane

PMID:26460541[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:26460541[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:26460541[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0031156

regulation of sorocarp development

PMID:26460541[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:1903664

regulation of asexual reproduction

PMID:26460541[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0031932

TORC2 complex

PMID:16079174[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q54D08

C

Seeded From UniProt

complete

involved_in

GO:0038202

TORC1 signaling

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0021796
PANTHER:PTN000124327
PomBase:SPBC216.07c
UniProtKB:P42345

P

Seeded From UniProt

complete

part_of

GO:0031932

TORC2 complex

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0021796
PANTHER:PTN000124327
PomBase:SPBC30D10.10c
UniProtKB:P42345
WB:WBGene00002583
dictyBase:DDB_G0281569

C

Seeded From UniProt

complete

part_of

GO:0031931

TORC1 complex

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0021796
MGI:MGI:1928394
PANTHER:PTN000124327
PomBase:SPBC216.07c
RGD:68371
UniProtKB:P42345
WB:WBGene00002583

C

Seeded From UniProt

complete

involved_in

GO:0016242

negative regulation of macroautophagy

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0021796
MGI:MGI:1928394
PANTHER:PTN000124327
UniProtKB:P42345

P

Seeded From UniProt

complete

involved_in

GO:0010507

negative regulation of autophagy

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1928394
PANTHER:PTN000124327
PomBase:SPBC216.07c
RGD:68371
SGD:S000001686
SGD:S000003827
UniProtKB:P42345
UniProtKB:Q9FR53

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0045035
FB:FBgn0053554
MGI:MGI:104779
MGI:MGI:1928394
PANTHER:PTN000124197
RGD:1593265
RGD:68371
SGD:S000000340
SGD:S000001141
SGD:S000003827
UniProtKB:P78527
UniProtKB:Q13315
UniProtKB:Q96Q15
UniProtKB:Q9FR53
UniProtKB:Q9Y4A5
WB:WBGene00000226
WB:WBGene00007028

C

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1928394
PANTHER:PTN000124327
PomBase:SPBC216.07c
PomBase:SPBC30D10.10c
RGD:68371
SGD:S000001686
SGD:S000003827
UniProtKB:P42345

F

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004674

P

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004674

P

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004674

P

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR026683

F

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR018936
InterPro:IPR036940

F

Seeded From UniProt

complete

enables

GO:0044877

protein-containing complex binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009076
InterPro:IPR036738

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0007049

cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0131

P

Seeded From UniProt

complete

involved_in

GO:0006935

chemotaxis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0145

P

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0723

F

Seeded From UniProt

complete

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Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Swer, PB et al. (2016) Overexpression of TOR (target of rapamycin) inhibits cell proliferation in Dictyostelium discoideum. J. Basic Microbiol. 56 510-9 PubMed GONUTS page
  2. ↑ Lee, S et al. (2005) TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium. Mol. Biol. Cell 16 4572-83 PubMed GONUTS page
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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