DEIRA:DPO1

Species (Taxon ID)	Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 /LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422). (243230)
Gene Name(s)	polA
Protein Name(s)	DNA polymerase I POL I
External Links
UniProt	P52027
EMBL	L14581 AE000513
PIR	A40597
RefSeq	NP_295430.1
ProteinModelPortal	P52027
STRING	243230.DR_1707
PRIDE	P52027
EnsemblBacteria	AAF11264
GeneID	1800388
KEGG	dra:DR_1707
PATRIC	21631046
eggNOG	COG0258
HOGENOM	HOG000020997
InParanoid	P52027
KO	K02335
OMA	KANRPPM
OrthoDB	EOG6SJJH7
BioCyc	DRAD243230:GH46-1738-MONOMER
Proteomes	UP000002524
GO	GO:0003677 GO:0003887 GO:0004527 GO:0001882 GO:0006281 GO:0006261
Gene3D	3.30.420.10 3.40.50.1010
InterPro	IPR020046 IPR020045 IPR002421 IPR019760 IPR001098 IPR018320 IPR002298 IPR008918 IPR003583 IPR029060 IPR012337 IPR015361
Pfam	PF01367 PF02739 PF00476 PF09281
PRINTS	PR00868
SMART	SM00475 SM00278 SM00279 SM00482
SUPFAM	SSF47807 SSF53098 SSF88723
TIGRFAMs	TIGR00593
PROSITE	PS00447

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
	GO:0003887	DNA-directed DNA polymerase activity	PMID:8501062^[1]	ECO:0000315			F	An activity gel assay showed that mutant strains were deficient in DNA polymerase activity. (see figure 6)	complete
enables	GO:0008409	5'-3' exonuclease activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10746 PANTHER:PTN000015249	F	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10746 PANTHER:PTN000015328	P	Seeded From UniProt	complete
involved_in	GO:0006261	DNA-dependent DNA replication	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10746 PANTHER:PTN000015249	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10746 PANTHER:PTN000015249	C	Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10746 MGI:MGI:2155399 PANTHER:PTN000015249 UniProtKB:O75417 UniProtKB:P52027 UniProtKB:Q6Z4T5 UniProtKB:Q7Z5Q5	F	Seeded From UniProt	complete
involved_in	GO:0071897	DNA biosynthetic process	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0003887	P	Seeded From UniProt	complete
involved_in	GO:0071897	DNA biosynthetic process	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0003887	P	Seeded From UniProt	complete
involved_in	GO:0071897	DNA biosynthetic process	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0003887	P	Seeded From UniProt	complete
involved_in	GO:0071897	DNA biosynthetic process	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0003887	P	Seeded From UniProt	complete
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0008409	P	Seeded From UniProt	complete
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004527	P	Seeded From UniProt	complete
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004518	P	Seeded From UniProt	complete
enables	GO:0001882	nucleoside binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015361	F	Seeded From UniProt	complete
enables	GO:0003676	nucleic acid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR036397	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001098 InterPro:IPR002421 InterPro:IPR008918 InterPro:IPR020045 InterPro:IPR020046	F	Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008918 InterPro:IPR020045	F	Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001098 InterPro:IPR002298 InterPro:IPR015361 InterPro:IPR018320 InterPro:IPR019760	F	Seeded From UniProt	complete
involved_in	GO:0006260	DNA replication	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001098 InterPro:IPR015361 InterPro:IPR018320 InterPro:IPR019760	P	Seeded From UniProt	complete
involved_in	GO:0006261	DNA-dependent DNA replication	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002298	P	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015361	P	Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.7.7	F	Seeded From UniProt	complete
involved_in	GO:0006260	DNA replication	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0235	P	Seeded From UniProt	complete
enables	GO:0004518	nuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0540	F	Seeded From UniProt	complete
enables	GO:0016779	nucleotidyltransferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0548	F	Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0239	F	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P	Seeded From UniProt	complete
enables	GO:0004527	exonuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0269	F	Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F	Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Gutman, PD et al. (1993) Identification, sequencing, and targeted mutagenesis of a DNA polymerase gene required for the extreme radioresistance of Deinococcus radiodurans. J. Bacteriol. 175 3581-90 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:8501062-1] Gutman, PD et al. (1993) Identification, sequencing, and targeted mutagenesis of a DNA polymerase gene required for the extreme radioresistance of Deinococcus radiodurans. J. Bacteriol. 175 3581-90 PubMed GONUTS page

[PMID:21873635-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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DEIRA:DPO1

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