DANRE:TBX20

Species (Taxon ID)	Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s)	tbx20
Protein Name(s)	T-box transcription factor TBX20 T-box protein 20 H15-related T-box transcription factor hrT
External Links
UniProt	Q9I9K7
EMBL	AF239664 AF253325
RefSeq	NP_571581.1
UniGene	Dr.8231
ProteinModelPortal	Q9I9K7
SMR	Q9I9K7
Ensembl	ENSDART00000017185
GeneID	57936
KEGG	dre:57936
CTD	57057
ZFIN	ZDB-GENE-000427-7
eggNOG	NOG272513
GeneTree	ENSGT00760000118897
HOGENOM	HOG000286000
HOVERGEN	HBG067710
InParanoid	Q9I9K7
KO	K10185
OrthoDB	EOG7GN2PM
PhylomeDB	Q9I9K7
NextBio	20891950
PRO	PR:Q9I9K7
Proteomes	UP000000437
Bgee	Q9I9K7
GO	GO:0005634 GO:0003677 GO:0003700 GO:0007275 GO:0006351
Gene3D	2.60.40.820
InterPro	IPR008967 IPR001699 IPR018186
PANTHER	PTHR11267
Pfam	PF00907
PRINTS	PR00937
SMART	SM00425
SUPFAM	SSF49417
PROSITE	PS01283 PS01264 PS50252

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0060043	regulation of cardiac muscle cell proliferation	PMID:27907103^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-MRPHLNO-171219-2	P	Seeded From UniProt	complete
involved_in	GO:0060043	regulation of cardiac muscle cell proliferation	PMID:27907103^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-171221-1	P	Seeded From UniProt	complete
involved_in	GO:0060038	cardiac muscle cell proliferation	PMID:27940156^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:18407257^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-MRPHLNO-070226-1	P	Seeded From UniProt	complete
involved_in	GO:0035844	cloaca development	PMID:16672335^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-MRPHLNO-070226-1	P	Seeded From UniProt	complete
involved_in	GO:0035162	embryonic hemopoiesis	PMID:12397116^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-MRPHLNO-070226-1	P	Seeded From UniProt	complete
involved_in	GO:0035050	embryonic heart tube development	PMID:12397116^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-MRPHLNO-070226-2	P	Seeded From UniProt	complete
involved_in	GO:0035050	embryonic heart tube development	PMID:12397116^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-MRPHLNO-070226-1	P	Seeded From UniProt	complete
involved_in	GO:0007507	heart development	PMID:27940156^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-170309-3	P	Seeded From UniProt	complete
involved_in	GO:0007507	heart development	PMID:27907103^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-MRPHLNO-171219-3	P	Seeded From UniProt	complete
involved_in	GO:0007507	heart development	PMID:27907103^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-MRPHLNO-171219-2	P	Seeded From UniProt	complete
involved_in	GO:0007507	heart development	PMID:27907103^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-171221-1	P	Seeded From UniProt	complete
involved_in	GO:0007507	heart development	PMID:10906473^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0007507	heart development	PMID:10656766^[7]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0003313	heart rudiment development	PMID:27940156^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-170309-3	P	Seeded From UniProt	complete
involved_in	GO:0001947	heart looping	PMID:12397116^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-MRPHLNO-070226-1	P	Seeded From UniProt	complete
involved_in	GO:0001570	vasculogenesis	PMID:12397116^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-MRPHLNO-070226-1	P	Seeded From UniProt	complete
involved_in	GO:0001568	blood vessel development	PMID:12397116^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-MRPHLNO-070226-1	P	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001699 InterPro:IPR008967 InterPro:IPR018186 InterPro:IPR036960	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001699 InterPro:IPR018186 InterPro:IPR036960	C	Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001699 InterPro:IPR008967 InterPro:IPR018186 InterPro:IPR036960	P	Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Just, S et al. (2016) Tbx20 Is an Essential Regulator of Embryonic Heart Growth in Zebrafish. PLoS ONE 11 e0167306 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Lu, F et al. (2017) Tbx20 drives cardiac progenitor formation and cardiomyocyte proliferation in zebrafish. Dev. Biol. 421 139-148 PubMed GONUTS page
↑ Qu, X et al. (2008) Ndrg4 is required for normal myocyte proliferation during early cardiac development in zebrafish. Dev. Biol. 317 486-96 PubMed GONUTS page
↑ Pyati, UJ et al. (2006) Sustained Bmp signaling is essential for cloaca development in zebrafish. Development 133 2275-84 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 Szeto, DP et al. (2002) HrT is required for cardiovascular development in zebrafish. Development 129 5093-101 PubMed GONUTS page
↑ Ahn, DG et al. (2000) tbx20, a new vertebrate T-box gene expressed in the cranial motor neurons and developing cardiovascular structures in zebrafish. Mech. Dev. 95 253-8 PubMed GONUTS page
↑ Griffin, KJ et al. (2000) A conserved role for H15-related T-box transcription factors in zebrafish and Drosophila heart formation. Dev. Biol. 218 235-47 PubMed GONUTS page

[PMID:27907103-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Just, S et al. (2016) Tbx20 Is an Essential Regulator of Embryonic Heart Growth in Zebrafish. PLoS ONE 11 e0167306 PubMed GONUTS page

[PMID:27940156-2] 2.0 ^2.1 ^2.2 Lu, F et al. (2017) Tbx20 drives cardiac progenitor formation and cardiomyocyte proliferation in zebrafish. Dev. Biol. 421 139-148 PubMed GONUTS page

[PMID:18407257-3] Qu, X et al. (2008) Ndrg4 is required for normal myocyte proliferation during early cardiac development in zebrafish. Dev. Biol. 317 486-96 PubMed GONUTS page

[PMID:16672335-4] Pyati, UJ et al. (2006) Sustained Bmp signaling is essential for cloaca development in zebrafish. Development 133 2275-84 PubMed GONUTS page

[PMID:12397116-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 Szeto, DP et al. (2002) HrT is required for cardiovascular development in zebrafish. Development 129 5093-101 PubMed GONUTS page

[PMID:10906473-6] Ahn, DG et al. (2000) tbx20, a new vertebrate T-box gene expressed in the cranial motor neurons and developing cardiovascular structures in zebrafish. Mech. Dev. 95 253-8 PubMed GONUTS page

[PMID:10656766-7] Griffin, KJ et al. (2000) A conserved role for H15-related T-box transcription factors in zebrafish and Drosophila heart formation. Dev. Biol. 218 235-47 PubMed GONUTS page

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DANRE:TBX20

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