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DANRE:S4TLP4

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) znf219 (ECO:0000313 with ZFIN:ZDB-GENE-110623-1)
Protein Name(s) Znf219-like protein (ECO:0000313 with EMBL:AGE89832.1)
External Links
UniProt S4TLP4
EMBL JX141438
RefSeq NP_001277346.1
GeneID 102997060
KEGG dre:102997060
CTD 51222
ZFIN ZDB-GENE-110623-1
GO GO:0046872
GO:0003676
GO:0030903
Gene3D 3.30.160.60
InterPro IPR007087
IPR015880
IPR013087
Pfam PF00096
SMART SM00355
PROSITE PS00028
PS50157

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0001077

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription

PMID:24155663[1]

ECO:0000315

F

Figure 6A shows that in mutants who express the Znf219-Like protein, activity at the promotor of the col2a1 gene is substantially increased when compared to the wild-type control.

complete
CACAO 9686

enables

GO:0001228

DNA-binding transcription activator activity, RNA polymerase II-specific

PMID:24155663[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

occurs_at:(SO:0001952)

Seeded From UniProt

complete

involved_in

GO:0030903

notochord development

PMID:24155663[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-131220-4

P

Seeded From UniProt

complete

involved_in

GO:0030903

notochord development

PMID:24155663[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-131220-3

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0001228

P

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013087

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Lien, HW et al. (2013) A novel zinc finger protein 219-like (ZNF219L) is involved in the regulation of collagen type 2 alpha 1a (col2a1a) gene expression in zebrafish notochord. Int. J. Biol. Sci. 9 872-86 PubMed GONUTS page