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DANRE:Q9PTF9

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) No Information Provided.
Protein Name(s) Bone morphogenetic protein 7 (ECO:0000313 with EMBL:AAF17558.1)

Uncharacterized protein (ECO:0000313 with Ensembl:ENSDARP00000017352)

External Links
UniProt Q9PTF9
EMBL CR925817
CU633826
AF201379
RefSeq NP_571396.1
UniGene Dr.77644
SMR Q9PTF9
Ensembl ENSDART00000016472
GeneID 30584
KEGG dre:30584
CTD 30584
ZFIN ZDB-GENE-000208-25
GeneTree ENSGT00760000118883
HOGENOM HOG000249476
HOVERGEN HBG004860
KO K16621
OMA YENETFH
PhylomeDB Q9PTF9
TreeFam TF316134
Reactome REACT_219441
NextBio 20806954
Proteomes UP000000437
GO GO:0005576
GO:0046982
GO:0042803
GO:0030509
GO:0003303
GO:0007368
GO:0048264
GO:0009953
GO:0003143
GO:0040007
GO:0001947
GO:0042664
GO:0036342
GO:0006461
Gene3D 2.10.90.10
InterPro IPR029034
IPR001839
IPR001111
IPR015615
IPR017948
PANTHER PTHR11848
Pfam PF00019
PF00688
SMART SM00204
SUPFAM SSF57501
PROSITE PS00250
PS51362

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001947

heart looping

PMID:9334285[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1043

P

Seeded From UniProt

complete

GO:0003143

embryonic heart tube morphogenesis

PMID:9334285[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1043

P

Seeded From UniProt

complete

GO:0003303

BMP signaling pathway involved in heart jogging

PMID:9334285[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1043

P

Seeded From UniProt

complete

GO:0005125

cytokine activity

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218063

F

Seeded From UniProt

complete

GO:0005160

transforming growth factor beta receptor binding

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218063

F

Seeded From UniProt

complete

GO:0005576

extracellular region

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

GO:0005615

extracellular space

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218063

C

Seeded From UniProt

complete

GO:0006461

protein complex assembly

PMID:19377468[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050216-1

P

Seeded From UniProt

complete

GO:0007368

determination of left/right symmetry

PMID:9334285[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1043

P

Seeded From UniProt

complete

GO:0008083

growth factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001111
InterPro:IPR001839
InterPro:IPR017948

F

Seeded From UniProt

complete

GO:0008083

growth factor activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0339

F

Seeded From UniProt

complete

GO:0009953

dorsal/ventral pattern formation

PMID:11748837[3]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-100422-2

P

Seeded From UniProt

complete

GO:0009953

dorsal/ventral pattern formation

PMID:11748837[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1043

P

Seeded From UniProt

complete

GO:0009953

dorsal/ventral pattern formation

PMID:11969259[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1043

P

Seeded From UniProt

complete

GO:0009953

dorsal/ventral pattern formation

PMID:9676195[5]

IEP: Inferred from Expression Pattern

P

Seeded From UniProt

complete

GO:0010862

positive regulation of pathway-restricted SMAD protein phosphorylation

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218063

P

Seeded From UniProt

complete

GO:0030509

BMP signaling pathway

PMID:19377468[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050216-1

P

Seeded From UniProt

complete

GO:0030509

BMP signaling pathway

PMID:9676195[5]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0036342

post-anal tail morphogenesis

PMID:21610036[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1043

P

Seeded From UniProt

complete

GO:0040007

growth

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001111

P

Seeded From UniProt

complete

GO:0042664

negative regulation of endodermal cell fate specification

PMID:16672336[7]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-980526-474
ZFIN:ZDB-GENE-980528-2059

P

Seeded From UniProt

complete

GO:0042803

protein homodimerization activity

PMID:19377468[2]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0042981

regulation of apoptotic process

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218063

P

Seeded From UniProt

complete

GO:0043408

regulation of MAPK cascade

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218063

P

Seeded From UniProt

complete

GO:0046982

protein heterodimerization activity

PMID:19377468[2]

IPI: Inferred from Physical Interaction

UniProtKB:O13108

F

Seeded From UniProt

complete

GO:0048264

determination of ventral identity

PMID:11222140[8]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0048264

determination of ventral identity

PMID:11222140[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-960

P

Seeded From UniProt

complete

GO:0048264

determination of ventral identity

PMID:11477698[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050902-3

P

Seeded From UniProt

complete

GO:0048264

determination of ventral identity

PMID:12601179[10]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1043

P

Seeded From UniProt

complete

GO:0048264

determination of ventral identity

PMID:16527746[11]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-050902-2
ZFIN:ZDB-MRPHLNO-050902-3

P

Seeded From UniProt

complete

GO:0048264

determination of ventral identity

PMID:16527746[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050902-3

P

Seeded From UniProt

complete

GO:0048468

cell development

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218063

P

Seeded From UniProt

complete

GO:0060395

SMAD protein signal transduction

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000218063

P

Seeded From UniProt

complete

GO:0070700

BMP receptor binding

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000932177

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Chen, JN et al. (1997) Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development 124 4373-82 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Little, SC & Mullins, MC (2009) Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis. Nat. Cell Biol. 11 637-43 PubMed GONUTS page
  3. 3.0 3.1 Grinblat, Y & Sive, H (2001) zic Gene expression marks anteroposterior pattern in the presumptive neurectoderm of the zebrafish gastrula. Dev. Dyn. 222 688-93 PubMed GONUTS page
  4. Wagner, DS & Mullins, MC (2002) Modulation of BMP activity in dorsal-ventral pattern formation by the chordin and ogon antagonists. Dev. Biol. 245 109-23 PubMed GONUTS page
  5. 5.0 5.1 Nguyen, VH et al. (1998) Ventral and lateral regions of the zebrafish gastrula, including the neural crest progenitors, are established by a bmp2b/swirl pathway of genes. Dev. Biol. 199 93-110 PubMed GONUTS page
  6. Yang, Y & Thorpe, C (2011) BMP and non-canonical Wnt signaling are required for inhibition of secondary tail formation in zebrafish. Development 138 2601-11 PubMed GONUTS page
  7. Poulain, M et al. (2006) Zebrafish endoderm formation is regulated by combinatorial Nodal, FGF and BMP signalling. Development 133 2189-200 PubMed GONUTS page
  8. 8.0 8.1 Bauer, H et al. (2001) The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/7 signal transduction during dorsoventral patterning of the zebrafish embryo. Development 128 849-58 PubMed GONUTS page
  9. Imai, Y & Talbot, WS (2001) Morpholino phenocopies of the bmp2b/swirl and bmp7/snailhouse mutations. Genesis 30 160-3 PubMed GONUTS page
  10. Sidi, S et al. (2003) Maternal induction of ventral fate by zebrafish radar. Proc. Natl. Acad. Sci. U.S.A. 100 3315-20 PubMed GONUTS page
  11. 11.0 11.1 Hogan, BM et al. (2006) Specification of the primitive myeloid precursor pool requires signaling through Alk8 in zebrafish. Curr. Biol. 16 506-11 PubMed GONUTS page