GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
DANRE:PARK7
Contents
| Species (Taxon ID) | Danio rerio (Zebrafish) (Brachydanio rerio). (7955) | |
| Gene Name(s) | park7 (ECO:0000312 with EMBL:AAH83475.1) (synonyms: dj1 (ECO:0000312 with EMBL:ABI64158.1)) | |
| Protein Name(s) | Protein DJ-1
zDJ-1 Parkinson disease protein 7 homolog | |
| External Links | ||
| UniProt | Q5XJ36 | |
| EMBL | DQ882651 BC083475 | |
| RefSeq | NP_001005938.1 | |
| UniGene | Dr.85181 | |
| ProteinModelPortal | Q5XJ36 | |
| SMR | Q5XJ36 | |
| STRING | 7955.ENSDARP00000041530 | |
| MEROPS | C56.971 | |
| PRIDE | Q5XJ36 | |
| Ensembl | ENSDART00000041531 | |
| GeneID | 449674 | |
| KEGG | dre:449674 | |
| CTD | 11315 | |
| ZFIN | ZDB-GENE-041010-5 | |
| eggNOG | COG0693 | |
| GeneTree | ENSGT00390000001231 | |
| HOGENOM | HOG000063194 | |
| HOVERGEN | HBG053511 | |
| InParanoid | Q5XJ36 | |
| KO | K05687 | |
| OMA | MAGDHYK | |
| OrthoDB | EOG7CVPZX | |
| PhylomeDB | Q5XJ36 | |
| TreeFam | TF300119 | |
| NextBio | 20832773 | |
| PRO | PR:Q5XJ36 | |
| Proteomes | UP000000437 | |
| Bgee | Q5XJ36 | |
| GO | GO:0005737 GO:0045121 GO:0005739 GO:0005634 GO:0005886 GO:0003729 GO:0008233 GO:0042803 GO:0006914 GO:0070301 GO:0034599 GO:0006954 GO:0060548 GO:2000277 GO:0050821 GO:0043523 GO:0006979 GO:0007338 | |
| Gene3D | 3.40.50.880 | |
| InterPro | IPR029062 IPR006287 IPR002818 | |
| Pfam | PF01965 | |
| SUPFAM | SSF52317 | |
| TIGRFAMs | TIGR01383 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0106046 |
guanine deglycation, glyoxal removal |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0106045 |
guanine deglycation, methylglyoxal removal |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0106044 |
guanine deglycation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006281 |
DNA repair |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1903427 |
negative regulation of reactive oxygen species biosynthetic process |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042593 |
glucose homeostasis |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030073 |
insulin secretion |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
NOT|involved_in |
GO:0036530 |
protein deglycation, methylglyoxal removal |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
NOT|involved_in |
GO:0009438 |
methylglyoxal metabolic process |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
NOT|involved_in |
GO:0006517 |
protein deglycosylation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006517 |
protein deglycosylation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:2000277 |
positive regulation of oxidative phosphorylation uncoupler activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0070301 |
cellular response to hydrogen peroxide |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0060548 |
negative regulation of cell death |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0050821 |
protein stabilization |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043523 |
regulation of neuron apoptotic process |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0034599 |
cellular response to oxidative stress |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008233 |
peptidase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003729 |
mRNA binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006979 |
response to oxidative stress |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-090320-6 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0106046 |
guanine deglycation, glyoxal removal |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000111103 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0036529 |
protein deglycation, glyoxal removal |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000111103 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0036524 |
protein deglycase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG13272 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG13272 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2135637 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006914 |
autophagy |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008233 |
peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007338 |
single fertilization |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006954 |
inflammatory response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045121 |
membrane raft |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Baulac, S et al. (2009) Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains. Mol Neurodegener 4 12 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
c
g
m
n
p
- GO:0008233 ! peptidase activity
- GO:0005886 ! plasma membrane
- GO:2000277 ! positive regulation of oxidative phosphorylation uncoupler activity
- GO:0036524 ! protein deglycase activity
- GO:0036530 ! protein deglycation, methylglyoxal removal
- GO:0006517 ! protein deglycosylation
- GO:0036529 ! protein deglycation, glyoxal removal
- GO:0042803 ! protein homodimerization activity
- GO:0050821 ! protein stabilization
- GO:0006508 ! proteolysis
r
