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DANRE:PARK7

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) park7 (ECO:0000312 with EMBL:AAH83475.1) (synonyms: dj1 (ECO:0000312 with EMBL:ABI64158.1))
Protein Name(s) Protein DJ-1

zDJ-1 Parkinson disease protein 7 homolog

External Links
UniProt Q5XJ36
EMBL DQ882651
BC083475
RefSeq NP_001005938.1
UniGene Dr.85181
ProteinModelPortal Q5XJ36
SMR Q5XJ36
STRING 7955.ENSDARP00000041530
MEROPS C56.971
PRIDE Q5XJ36
Ensembl ENSDART00000041531
GeneID 449674
KEGG dre:449674
CTD 11315
ZFIN ZDB-GENE-041010-5
eggNOG COG0693
GeneTree ENSGT00390000001231
HOGENOM HOG000063194
HOVERGEN HBG053511
InParanoid Q5XJ36
KO K05687
OMA MAGDHYK
OrthoDB EOG7CVPZX
PhylomeDB Q5XJ36
TreeFam TF300119
NextBio 20832773
PRO PR:Q5XJ36
Proteomes UP000000437
Bgee Q5XJ36
GO GO:0005737
GO:0045121
GO:0005739
GO:0005634
GO:0005886
GO:0003729
GO:0008233
GO:0042803
GO:0006914
GO:0070301
GO:0034599
GO:0006954
GO:0060548
GO:2000277
GO:0050821
GO:0043523
GO:0006979
GO:0007338
Gene3D 3.40.50.880
InterPro IPR029062
IPR006287
IPR002818
Pfam PF01965
SUPFAM SSF52317
TIGRFAMs TIGR01383

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003723

RNA binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0694

F

complete

GO:0003729

mRNA binding

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

F

complete

GO:0005634

nucleus

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0539

C

complete

GO:0005634

nucleus

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0191

C

complete

GO:0005634

nucleus

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

C

complete

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

complete

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

complete

GO:0005737

cytoplasm

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

C

complete

GO:0005739

mitochondrion

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0496

C

complete

GO:0005739

mitochondrion

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0173

C

complete

GO:0005739

mitochondrion

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

C

complete

GO:0006914

autophagy

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0072

P

complete

GO:0006950

response to stress

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0346

P

complete

GO:0006954

inflammatory response

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0395

P

complete

GO:0006979

response to oxidative stress

PMID:19243613[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-090320-6

P

complete

GO:0007338

single fertilization

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0278

P

complete

GO:0008233

peptidase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0645

F

complete

GO:0008233

peptidase activity

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

F

complete

GO:0016787

hydrolase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

complete

GO:0034599

cellular response to oxidative stress

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99LX0

P

complete

GO:0042803

protein homodimerization activity

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

F

complete

GO:0003723

RNA binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

GO:0043526

neuroprotection

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

P

complete

GO:0003729

mRNA binding

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

F

Seeded From UniProt

complete

GO:0050821

protein stabilization

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

P

complete

GO:0005634

nucleus

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

C

Seeded From UniProt

complete

GO:0060548

negative regulation of cell death

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

P

complete

GO:0005634

nucleus

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

GO:0070301

cellular response to hydrogen peroxide

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

P

complete

GO:0005634

nucleus

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

GO:2000277

positive regulation of oxidative phosphorylation uncoupler activity

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99LX0

P

complete

GO:0005737

cytoplasm

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

GO:0005739

mitochondrion

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

C

Seeded From UniProt

complete

GO:0005739

mitochondrion

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0496

C

Seeded From UniProt

complete

GO:0005739

mitochondrion

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0173

C

Seeded From UniProt

complete

GO:0005886

plasma membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

Seeded From UniProt

complete

GO:0005886

plasma membrane

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

GO:0006508

proteolysis

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0645

P

Seeded From UniProt

complete

GO:0006517

protein deglycosylation

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

P

Seeded From UniProt

complete

GO:0006914

autophagy

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0072

P

Seeded From UniProt

complete

GO:0006954

inflammatory response

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0395

P

Seeded From UniProt

complete

GO:0006979

response to oxidative stress

PMID:19243613[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-090320-6

P

Seeded From UniProt

complete

GO:0007338

single fertilization

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0278

P

Seeded From UniProt

complete

GO:0008233

peptidase activity

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

F

Seeded From UniProt

complete

GO:0008233

peptidase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0645

F

Seeded From UniProt

complete

GO:0016020

membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

GO:0016787

hydrolase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

GO:0034599

cellular response to oxidative stress

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99LX0

P

Seeded From UniProt

complete

GO:0042803

protein homodimerization activity

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

F

Seeded From UniProt

complete

GO:0043523

regulation of neuron apoptotic process

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

P

Seeded From UniProt

complete

GO:0045121

membrane raft

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0370

C

Seeded From UniProt

complete

GO:0050821

protein stabilization

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

P

Seeded From UniProt

complete

GO:0060548

negative regulation of cell death

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

P

Seeded From UniProt

complete

GO:0070301

cellular response to hydrogen peroxide

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99497

P

Seeded From UniProt

complete

GO:2000277

positive regulation of oxidative phosphorylation uncoupler activity

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q99LX0

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Baulac, S et al. (2009) Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains. Mol Neurodegener 4 12 PubMed GONUTS page