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DANRE:N2F1B

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) nr2f1b (ECO:0000312 with ZFIN:ZDB-GENE-040426-1438) (synonyms: nr2f1l (ECO:0000312 with ZFIN:ZDB-GENE-040426-1438))
Protein Name(s) Nuclear receptor subfamily 2 group F member 1-B (ECO:0000312 with EMBL:AAH56748.1)

COUP transcription factor 1-B (ECO:0000303 with PMID:17997606[1]) COUP-TFalpha-B (ECO:0000303 with PMID:17997606[1])

External Links
UniProt Q6PH18
EMBL BC056748
BC065651
RefSeq NP_956886.1
XP_005155493.1
UniGene Dr.86046
ProteinModelPortal Q6PH18
SMR Q6PH18
STRING 7955.ENSDARP00000010118
PaxDb Q6PH18
Ensembl ENSDART00000027242
GeneID 393564
KEGG dre:393564
CTD 393564
ZFIN ZDB-GENE-040426-1438
eggNOG KOG3575
ENOG410XRZC
GeneTree ENSGT00760000118948
HOGENOM HOG000260820
HOVERGEN HBG005606
InParanoid Q6PH18
OMA FMENIRI
OrthoDB EOG72RMZ5
PhylomeDB Q6PH18
TreeFam TF352097
NextBio 20814585
PRO PR:Q6PH18
Proteomes UP000000437
Bgee Q6PH18
GO GO:0005634
GO:0004879
GO:0043565
GO:0003707
GO:0008270
GO:0006351
Gene3D 1.10.565.10
3.30.50.10
InterPro IPR003068
IPR000536
IPR001723
IPR001628
IPR013088
Pfam PF00104
PF00105
PRINTS PR01282
PR00398
PR00047
SMART SM00430
SM00399
SUPFAM SSF48508
PROSITE PS00031
PS51030

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001723
InterPro:IPR003068

F

Seeded From UniProt

GO:0003677

DNA binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

Seeded From UniProt

GO:0003700

transcription factor activity, sequence-specific DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001628

F

Seeded From UniProt

GO:0003707

steroid hormone receptor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001723

F

Seeded From UniProt

GO:0004879

RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003068

F

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001628
InterPro:IPR001723
InterPro:IPR003068

C

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

GO:0006351

transcription, DNA-templated

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

Seeded From UniProt

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000536
InterPro:IPR001628
InterPro:IPR001723
InterPro:IPR003068
InterPro:IPR013088

P

Seeded From UniProt

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

Seeded From UniProt

GO:0008270

zinc ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001628
InterPro:IPR013088

F

Seeded From UniProt

GO:0030522

intracellular receptor signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003068

P

Seeded From UniProt

GO:0043401

steroid hormone mediated signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000536

P

Seeded From UniProt

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001628

F

Seeded From UniProt

GO:0046872

metal ion binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

Seeded From UniProt

GO:1901342

regulation of vasculature development

PMID:26572615[2]

IMP: Inferred from Mutant Phenotype

P

Figure 2 shows nr2flb mutants have defects in vascular development.

complete
CACAO 11711

GO:0072358

cardiovascular system development

PMID:26572615[2]

IMP: Inferred from Mutant Phenotype

P

Figure 2 shows nr2flb mutants have defects in vascular development.

complete
CACAO 11712

GO:0035476

angioblast cell migration

PMID:26572615[2]

IMP: Inferred from Mutant Phenotype

P

Figure 5 shows decrease ISV angioblast cell migration in nr2f1b mutants.

complete
CACAO 11713

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Bertrand, S et al. (2007) Unexpected novel relational links uncovered by extensive developmental profiling of nuclear receptor expression. PLoS Genet. 3 e188 PubMed GONUTS page
  2. 2.0 2.1 2.2 Li, RF et al. (2015) Nr2f1b control venous specification and angiogenic patterning during zebrafish vascular development. J. Biomed. Sci. 22 104 PubMed GONUTS page