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DANRE:N2F1B

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) nr2f1b (ECO:0000312 with ZFIN:ZDB-GENE-040426-1438) (synonyms: nr2f1l (ECO:0000312 with ZFIN:ZDB-GENE-040426-1438))
Protein Name(s) Nuclear receptor subfamily 2 group F member 1-B (ECO:0000312 with EMBL:AAH56748.1)

COUP transcription factor 1-B (ECO:0000303 with PMID:17997606[1]) COUP-TFalpha-B (ECO:0000303 with PMID:17997606[1])

External Links
UniProt Q6PH18
EMBL BC056748
BC065651
RefSeq NP_956886.1
XP_005155493.1
UniGene Dr.86046
ProteinModelPortal Q6PH18
SMR Q6PH18
STRING 7955.ENSDARP00000010118
PaxDb Q6PH18
Ensembl ENSDART00000027242
GeneID 393564
KEGG dre:393564
CTD 393564
ZFIN ZDB-GENE-040426-1438
eggNOG KOG3575
ENOG410XRZC
GeneTree ENSGT00760000118948
HOGENOM HOG000260820
HOVERGEN HBG005606
InParanoid Q6PH18
OMA FMENIRI
OrthoDB EOG72RMZ5
PhylomeDB Q6PH18
TreeFam TF352097
NextBio 20814585
PRO PR:Q6PH18
Proteomes UP000000437
Bgee Q6PH18
GO GO:0005634
GO:0004879
GO:0043565
GO:0003707
GO:0008270
GO:0006351
Gene3D 1.10.565.10
3.30.50.10
InterPro IPR003068
IPR000536
IPR001723
IPR001628
IPR013088
Pfam PF00104
PF00105
PRINTS PR01282
PR00398
PR00047
SMART SM00430
SM00399
SUPFAM SSF48508
PROSITE PS00031
PS51030

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:1901342

regulation of vasculature development

PMID:26572615[2]

ECO:0000315

P

Figure 2 shows nr2flb mutants have defects in vascular development.

complete
CACAO 11711

GO:0072358

cardiovascular system development

PMID:26572615[2]

ECO:0000315

P

Figure 2 shows nr2flb mutants have defects in vascular development.

complete
CACAO 11712

GO:0035476

angioblast cell migration

PMID:26572615[2]

ECO:0000315

P

Figure 5 shows decrease ISV angioblast cell migration in nr2f1b mutants.

complete
CACAO 11713

involved_in

GO:0060841

venous blood vessel development

PMID:26572615[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-160211-4

P

Seeded From UniProt

complete

involved_in

GO:0001944

vasculature development

PMID:26572615[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-160211-4

P

Seeded From UniProt

complete

involved_in

GO:0001944

vasculature development

PMID:26572615[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-160211-3

P

Seeded From UniProt

complete

involved_in

GO:0001944

vasculature development

PMID:26572615[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-160211-2

P

Seeded From UniProt

complete

involved_in

GO:0043401

steroid hormone mediated signaling pathway

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003707

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001723

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628

F

Seeded From UniProt

complete

enables

GO:0003707

steroid hormone receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001723

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628
InterPro:IPR001723

C

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628
InterPro:IPR001723
InterPro:IPR013088

P

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628
InterPro:IPR013088

F

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001628

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Bertrand, S et al. (2007) Unexpected novel relational links uncovered by extensive developmental profiling of nuclear receptor expression. PLoS Genet. 3 e188 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Li, RF et al. (2015) Nr2f1b control venous specification and angiogenic patterning during zebrafish vascular development. J. Biomed. Sci. 22 104 PubMed GONUTS page