GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

Category:Team Chazz Rable

From GONUTS
Jump to: navigation, search
StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
HUMAN:V2RBMartinezVaz02, Team Chazz Rable2017-06-15 15:48:53 CDTGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (P)other:23762448ECO:0000315 mutant phenotype evidence used in manual assertion

The evidence comes from a paper by Amstrong (2013). Two mutants of the human vasopressin receptor, R181C and M311V, were characterized and shown to have loss of function. The mutants showed reduced signaling downstream of the pathway as demonstrated by lower levels of cAMP. The data is shown in Figure 1 A&B.

challenge

What do the icons mean in the status column?

assessment icons.jpg

Pages in category "Team Chazz Rable"

The following 6 pages are in this category, out of 6 total.


Jump to pages starting with: 5 B D E M O