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Category:GO:1990788 ! GLI-SUFU complex
name: GLI-SUFU complex
namespace: cellular_component
def: "A protein repressing GLI's transcription factor activity when SMO signaling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins." [GOC:bhm, PMID:24311597]
comment: An example of this is SUFU in human (Q9UMX1) in PMID:24311597 (inferred from direct assay).
is_a: GO:0032991 ! protein-containing complex
relationship: part_of: GO:0005829 ! cytosol
AmiGO
<GOterm>GO:1990788</GOterm>
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