name: titin-telethonin complex
The contents of this box are automatically generated. You can help by adding information to the "Notes"
def: "A protein complex formed between the N-terminus of the giant sarcomeric filament protein titin and the Z-disk ligand, telethonin. The complex is part of the Z-disk of the skeletal and cardiac sarcomere. Telethonin binding to titin might be essential for the initial assembly, stabilization and functional integrity of the titin filament, and hence important for muscle contraction relaxation in mature myofibrils." [GOC:ame, PMID:16407954]
comment: An example of this are TTN and TCAP in human (UniProt symbols Q8WZ42 and O15273 respectively) in PMID:16407954 (inferred from direct assay).
synonym: "Titin-Tcap complex" RELATED 
is_a: GO:0032991 ! protein-containing complex
relationship: part_of: GO:0030018 ! Z disc
Gene Ontology Home
See Help:References for how to manage references in GONUTS.
This category currently contains no pages or media.