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Category:GO:1990726 ! Lsm1-7-Pat1 complex
name: Lsm1-7-Pat1 complex
namespace: cellular_component
def: "A conserved, heteroheptameric, cytoplasmic protein complex composed of Lsm1, Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Pat1, or orthologs thereof, that shows a strong binding preference for oligoadenylated RNAs over polyadenylated RNAs. May bind further associated proteins. Facilitates the deadenylation-dependent decapping of mRNA in the P-body thereby regulating mRNA decay and subsequent degradation by the 5' to 3' pathway." [GOC:bhm, GOC:krc, PMID:19121818, PMID:23620288, PMID:24139796, PMID:27627834, PMID:28768202]
is_a: GO:0120114 ! Sm-like protein family complex
AmiGO
<GOterm>GO:1990726</GOterm>
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Pages in category "GO:1990726 ! Lsm1-7-Pat1 complex"
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