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Category:GO:1990633 ! mutator focus
name: mutator focus
namespace: cellular_component
def: "A type of punctate focus localized to the perinuclear region of germline cytoplasm in C. elegans. Mutator foci are required for RNA interference (RNAi) and serve as sites of small inhibitory RNA (siRNA) amplification. As such, proteins that localize to mutator foci include RNA-directed RNA polymerases (RdRPs) and beta-nucleotidyltransferases. Mutator foci are distinct from, but adjacent to or partially overlap, P granules." [GOC:kmv, PMID:22713602, PMID:25635455]
is_a: GO:0036464 ! cytoplasmic ribonucleoprotein granule
relationship: part_of: GO:0048471 ! perinuclear region of cytoplasm
AmiGO
<GOterm>GO:1990633</GOterm>
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Pages in category "GO:1990633 ! mutator focus"
The following 3 pages are in this category, out of 3 total.
