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Category:GO:1990130 ! GATOR1 complex
name: GATOR1 complex
namespace: cellular_component
def: "A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, the GATOR1 complex consists of DEPDC5, NPRL2, and NPRL3. In S. cerevisiae, this complex is referred to as SEACIT and contains the Iml1p, Npr2p, and Npr3p proteins." [GOC:krc, GOC:rb, PMID:21900499, PMID:23723238, PMID:23974112, PMID:25934700, PMID:28199306, PMID:29199950]
comment: The Rag GTPase complex corresponds to Gtr1-Gtr2 GTPase complex ; GO:1990131.
synonym: "IML1 complex" EXACT []
synonym: "SEACIT complex" EXACT []
is_a: GO:0032991 ! protein-containing complex
relationship: part_of: GO:0035859 ! Seh1-associated complex
AmiGO
<GOterm>GO:1990130</GOterm>
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