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Category:GO:0180022 ! RQC-trigger complex
name: RQC-trigger complex
namespace: cellular_component
def: "A ribosome disassembly complex which dissociates stalled ribsome subunits as part of the ribosome quality control pathway. RQT complex is composed of a RNA helicase-family protein yeast Rqt2 (human ASCC3), a ubiquitin-binding protein yeast Rqt3, (human ASCC2), and Rqt4 (human TRIP4). The human complex has an additional component protein ASCC1 and can act as a transcriptional coactivator by interacting with transcription factors such as NF-kappa B." [PMID:12077347, PMID:28757607, PMID:32099016]
synonym: "activating signal cointegrator 1 complex" EXACT []
synonym: "ASC-1 complex" EXACT [PMID:12077347]
synonym: "RQT complex" EXACT []
is_a: GO:0032991 ! protein-containing complex
AmiGO
<GOterm>GO:0180022</GOterm>
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