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Category:GO:0141176 ! gene silencing by piRNA-directed DNA methylation
name: gene silencing by piRNA-directed DNA methylation
namespace: biological_process
def: "A small RNA-based gene silencing process in which Piwi-associated RNAs (piRNAs) guide de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription." [PMID:32674113, PMID:38359823]
is_a: GO:0006346 ! DNA methylation-dependent constitutive heterochromatin formation
is_a: GO:0140966 ! piRNA-mediated heterochromatin formation
AmiGO
<GOterm>GO:0141176</GOterm>
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