Category:GO:0140493 ! very long-chain fatty acid beta-oxidation

name: very long-chain fatty acid beta-oxidation
namespace: biological_process
def: "A fatty acid beta-oxidation pathway acting on a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons. The partway stars with the conversion of an acyl-CoA to a trans-2-enoyl-CoA, catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively)." [GOC:ha, PMID:17028011, PMID:32169171]
comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
is_a: GO:0033540 ! fatty acid beta-oxidation using acyl-CoA oxidase
is_a: GO:0042760 ! very long-chain fatty acid catabolic process

AmiGO <GOterm>GO:0140493</GOterm>
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