Category:GO:0099526 ! presynapse to nucleus signaling pathway

name: presynapse to nucleus signaling pathway
namespace: biological_process
def: "The series of molecular signals that conveys information from the presynapse to the nucleus via cytoskeletal transport of a protein from a presynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications)." [GOC:dos, PMID:24317321, PMID:25652077]
comment: This class does not cover the cellular machinery (motor proteins, cargo-recognition proteins) that transports the signaling protein along the cytoskeleton towards the nucleus. For these cases, annotate to the appropriate transport/trafficking term.
subset: goslim_synapse
synonym: "presynaptic signaling to nucleus" EXACT []
is_a: GO:0098928 ! presynaptic signal transduction

AmiGO <GOterm>GO:0099526</GOterm>
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