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Category:GO:0097619 ! PTEX complex

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DAG for GO:0097619id: GO:0097619

name: PTEX complex
namespace: cellular_component
def: "A protein complex that acts as a protein trafficking machinery and is responsible for the export of proteins across the parasitophorous (symbiont-containing) vacuolar membrane and into the human host cell. The PTEX complex is located in the vacuole membrane. It is ATP-powered, and comprises heat shock protein 101 (HSP101; a ClpA/B-like ATPase from the AAA+ superfamily, of a type commonly associated with protein translocons), a parasite protein termed PTEX150, and exported protein 2 (EXP2). EXP2 is the potential channel, as it is the membrane-associated component of the core PTEX complex. Two other proteins, PTEX88 and thioredoxin 2 (TRX2), were also identified as PTEX components." [GOC:pr, PMID:19536257, PMID:25043010, PMID:25043043]
synonym: "Plasmodium translocon of exported proteins" RELATED []
is_a: GO:0032991 ! protein-containing complex
relationship: part_of: GO:0020005 ! symbiont-containing vacuole membrane

AmiGO <GOterm>GO:0097619</GOterm>
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Pages in category "GO:0097619 ! PTEX complex"

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