Category:GO:0097528 ! execution phase of necroptosis

name: execution phase of necroptosis
namespace: biological_process
def: "A stage of the necroptotic process that starts after a necroptotic signal has been relayed to the execution machinery. Key steps of the execution phase are swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. The execution phase ends when the cell has died." [GOC:mtg_apoptosis, PMID:20823910]
synonym: "execution phase of necroptotic process" EXACT []
synonym: "necroptosis" BROAD []
synonym: "necroptotic execution phase" EXACT []
is_a: GO:0009987 ! cellular process
relationship: part_of: GO:0070266 ! necroptotic process

AmiGO <GOterm>GO:0097528</GOterm>
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