GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Category:GO:0097071 ! interferon regulatory factor complex
name: interferon regulatory factor complex
def: "A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit." [GOC:cna, PMID:20043992]
synonym: "IRF complex" EXACT 
is_a: GO:0032991 ! protein-containing complex
Gene Ontology Home
The contents of this box are automatically generated. You can help by adding information to the "Notes"
See Help:References for how to manage references in GONUTS.
This category has the following 5 subcategories, out of 5 total.