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Category:GO:0097071 ! interferon regulatory factor complex

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DAG for GO:0097071id: GO:0097071

name: interferon regulatory factor complex
namespace: cellular_component
def: "A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit." [GOC:cna, PMID:20043992]
synonym: "IRF complex" EXACT []
is_a: GO:0032991 ! protein-containing complex

AmiGO <GOterm>GO:0097071</GOterm>
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