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Category:GO:0071986 ! Ragulator complex
name: Ragulator complex
namespace: cellular_component
alt_id: GO:0034448
alt_id: GO:0034449
def: "A vacuolar membrane-anchored guanine nucleotide exchange factor (GEF) complex for the Rag GTPases (Gtr1-Gtr2 GTPase complex GO:1990131) in TORC1 signaling pathway. In human, Ragulator is comprised of the membrane anchor subunit LAMTOR1 (Meh1p in S. cerevisiae, Lam1 in S. pombe), a GEF subunit LAMTOR2 ( Slm4 in S. cerevisiae , Lam2 in S. pombe ) , LAMTOR3 (no S. cerevisiae ortholog identified, Lam3 in S. pombe) , LAMTOR4 (no S. cerevisiae ortholog identified, Lam4 in S. pombe), and LAMTOR5 (no S. cerevisiae or S. pombe ortholog identified)." [GOC:vw, PMID:15989961, PMID:16732272, PMID:19177150, PMID:19748353, PMID:20381137, PMID:22980980, PMID:29199950]
synonym: "EGO complex" RELATED []
synonym: "EGO-GSE complex" RELATED []
synonym: "GSE complex" RELATED []
synonym: "GTPase-containing complex for Gap1p sorting in the endosome" RELATED []
synonym: "MAPKSP1/ROBLD3/C11orf59 complex" EXACT [GOC:mah]
synonym: "Rag GEF" EXACT []
is_a: GO:0032045 ! guanyl-nucleotide exchange factor complex
is_a: GO:0098796 ! membrane protein complex
relationship: part_of: GO:0005774 ! vacuolar membrane
AmiGO
<GOterm>GO:0071986</GOterm>
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