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Category:GO:0071751 ! secretory IgA immunoglobulin complex
name: secretory IgA immunoglobulin complex
namespace: cellular_component
def: "A polymeric IgA immunoglobulin complex that is complexed with one chain of secretory component (SC). Polymeric IgA is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component." [GOC:add, ISBN:0781765196, PMID:16362985]
comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. In human only the IgA1 isotype in the polymeric form is capable of becoming secretory IgA.
synonym: "secretory IgA antibody" EXACT [GOC:add]
synonym: "sIgA antibody" EXACT [GOC:add]
synonym: "sIgA1 antibody" NARROW [GOC:add]
is_a: GO:0071749 ! polymeric IgA immunoglobulin complex
AmiGO
<GOterm>GO:0071751</GOterm>
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