GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Category:GO:0071749 ! polymeric IgA immunoglobulin complex
name: polymeric IgA immunoglobulin complex
namespace: cellular_component
def: "A protein complex composed of two, three, or four monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through disulfide binded monomers of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196, PMID:16362985]
comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Dimeric IgA is by far the most common form of polymeric IgA. In human only the IgA1 isotype is capable of a polymeric forms.
synonym: "pIgA antibody" EXACT [GOC:add]
synonym: "pIgA1 antibody" NARROW [GOC:add]
synonym: "polymeric IgA antibody" EXACT [GOC:add]
synonym: "polymeric IgA1 antibody" NARROW [GOC:add]
is_a: GO:0071746 ! IgA immunoglobulin complex, circulating
AmiGO
<GOterm>GO:0071749</GOterm>
Gene Ontology Home
The contents of this box are automatically generated. You can help by adding information to the "Notes"
Usage Notes
References
See Help:References for how to manage references in GONUTS.
Child Terms
This category has the following 2 subcategories, out of 2 total.
